LCGC Europe: April 2016 Edit List
Issue Focus: ANALYTICA ISSUE: Annual review of New LC columns & Accessories; Annual Review of HPLC Systems and Accessories, Liquid Chromatography, Mass Spectrometry, Food Analysis, SFC, Sample Preparation
COLUMNS
Column Watch
Annual Review of New LC Columns and Accessories
David Bell
Our annual review of new liquid chromatography columns and accessories, introduced at Pittcon and other events.
LC Troubleshooting
Retention Time Drift—a Case Study
John W. Dolan
Retention times drop from one injection to the next. A systematic approach to troubleshooting can help to quickly identify the problem source.
Perspectives in Modern HPLC
New HPLC Systems and Related Products Introduced at Pittcon 2016: A Brief Review
Michael Dong
This installment highlights some of the new HPLC systems, modules, accessories, and related technology introduced at Pittcon this year.
MS—The Practical Art
Desorption and Ionization Mass Spectrometry in Research Laboratories
Giuseppe Astarita and Bindesh Shrestha
The past decade has brought exponential growth in the number of mass spectrometry (MS) ionization techniques based on desorption and ionization (DI) processes. Here, the three key applications for DI are discussed: rapid, in situ screening; direct analysis of extracted samples or of planar chromatography spots; and scanning samples along x and y axes.
The Essentials
BioChromatography Size Exclusion and Ion Exchange Techniques
A summary of what these techniques can tell us from a qualitative and quantitative perspective
ARTICLES
LC–MS-Compatible Approaches for the Quantitation of Limonin in Citrus Juice
Joshua E. Young, Joseph J. Pesek, Maria T. Matyska
Limonin was separated from other components in citrus juice sample matrices by reversed-phase chromatography with ultraviolet detection.
Magnetic Nanoparticles in Solid-Phase Extraction
Javier González-Sálamo1, Antonio V. Herrera-Herrera1, Chiara Fanali2, Javier Hernández-Borges1,*
1Departamento de Química, Unidad Departamental de Química Analítica, Facultad de Ciencias, Universidad de La Laguna (ULL). Avenida. Astrofísico Fco. Sánchez, s/nº. 38206 San Cristóbal de La Laguna, Tenerife, Islas Canarias, España.
2 Integrated Center of Research, Campus Bio-Medico University, Via Alvaro del Portillo 21, Rome, Italy.
The development of novel sorbents with high sorption capacity and high surface area and stability are among the current trends in Analytical Chemistry and m-NPs meet by far these characteristics. m-NPs fabrication frequently implies three different steps: the synthesis of the m-NP itself, the coating of this magnetic core and the further modification of the surface to obtain the desirable interaction. In order to provide a general idea of this topic, this article is aimed at providing an overview of m-NPs synthetic procedures, including their combination or coating with different organic or inorganic materials and their most relevant applications at the moment, though, as expected, interesting and challenging contributions on this topic are constantly being published.
The Role of SFC for the Purification of Pharmaceuticals?
Eric Francotte
Packed-column supercritical fluid chromatography (SFC) has become increasingly popular for chiral separations in recent years. The development of SFC has been driven by the many inherent advantages of the supercritical mobile phase (carbon dioxide) which include higher diffusivity, lower pressure drops, short equilibration times, reduction of solvent consumption and, in preparative applications, faster solvent removal. In addition to these technical advantages, lower solvent costs, less safety concerns with respect to flammability and toxicity, and reduced impact on the environment make SFC also an attractive separation technique.