In a placebo-controlled phase 2 study of patients with severe non-infectious uveitis involving the posterior segment, subcutaneous sarilumab (Kevzara, Sanofi/Regeneron) demonstrated promising therapeutic activity.
A retrospective chart review study of patients who received the fluocinolone acetonide 0.19 mg implant (Iluvien, Alimera Sciences) for diabetic macular edema shows its efficacy and safety when patients are selected per the FDA-approved indication. Compared with the pre-implant period, visual acuity was maintained or improved and there were reductions in both treatment burden and the amplitude of retinal thickness fluctuation.
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