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Formulary, A peer-reviewed drug management journal for managed care and hospital decision-makers
Part of the Modern Medicine Network

e-News

FormularyJournal.com

February 18, 2011

Formulary
Home Medication Safety FDA Actions Latest News Policy Watch Drug Watch
In This Issue
Oseltamivir oral suspension on back order
DMARD receipt variations in Medicare RA patients
ACIP revises 2011 adult immunization schedule
Cardio risks added to rosiglitazone label, medication guide
Herpes zoster vaccine on back order
Vascugel fast tracked
Therapy update
A review of peripherally acting mu-opioid
receptor antagonists

Survey

Last month’s survey results:

With healthcare reform creating an FDA approval pathway for biosimilar agents in the United States, what do you see as the primary implications of this from a managed care perspective in the next 3 years?
Click Here to Vote

No impact, as I don't see any changes occurring soon: 14.5%

Limited savings with only a small number of products and small number of manufacturers: 45%

Moderate savings with the introduction of several products at moderate discounting to innovator brands: 26%

Significant savings with several biosimilar options, significant discounts and enhanced rebating from innovator brands: 14.5%

This month we would like to know...

How does your health system handle new drug approvals?

1) We have a 6-month moratorium on newly FDA-approved drugs.

2) We have a 12-month moratorium on newly FDA-approved drugs.

3) If approved by the P&T committee, newly FDA-approved drugs can be added at anytime without restrictions.

4) If approved by the P&T committee, newly FDA-approved drugs can be added at anytime with step therapy or other modality to manage drug use and cost.

5) Other

Click Here to Vote

Digital Edition

Formulary Digital Edition View Current Edition Subscribe to the Digital Edition

Oseltamivir oral suspension on back order due to increased demand

Oseltamivir phosphate oral suspension (Tamiflu) is on back order due to increased demand, manufacturer Genentech announced. Read full article.

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Variations in DMARD receipt exist in Medicare managed care patients with RA

An analysis of data from more than 90,000 Medicare managed care enrollees who received care for rheumatoid arthritis found that more than one-third did not receive the recommended treatment with a disease-modifying antirheumatic drug, and that receipt varied by demographic factors, socioeconomic status, geographic location, and health plan, according to a study in JAMA. Read full article.

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ACIP revises adult immunization schedule for 2011

The Advisory Committee on Immunization Practices announces several changes to the recommended adult immunization schedule for 2011. Read full article.

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Rosiglitazone label and medication guide updated with cardiovascular risks

FDA has announced that the physician labeling and patient medication guide for rosiglitazone (Avandia, GlaxoSmithKline) have been changed to include information on cardiovascular risks (including death) of this agent. Read full article.

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Herpes zoster vaccine on back order

Less than 1 month after the Centers for Disease Control and Prevention’s Advisory Committee on Immunization Practices recommended that most Americans aged 60 years and older get vaccinated to prevent herpes zoster, the vaccine (Zostavax, Merck) is on back order. Read full article.

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FDA fast tracks Vascugel

FDA has granted fast-track designation to a novel endothelial cell-based therapy (Vascugel, Pervasis) for the prevention of hemodialysis access failure in patients with end-stage renal disease. Read full article.

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THERAPY UPDATE

A review of peripherally acting
mu-opioid receptor antagonists

This article reviews the emerging class of peripherally acting mu-opioid receptor antagonists and provides insight on formulary considerations when evaluating these agents. Read full article.

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Top 5 Web Stories

  1. Plaque psoriasis: A review of recent guidelines and pharmacologic therapies

  2. Technosphere insulin: An inhaled mealtime insulin for the treatment of type 1 and type 2 diabetes mellitus

  3. First-time generic approvals January 2011

  4. FDA Pipeline Preview, January 2011 (Ezogabine, Ticagrelor, Naltrexone SR/bupropion, Clostridium difficile vaccine, Elacytarabine, Glycerol phenylbutyrate, Perifosine, Cladribine Tablets, Florbetapir, ALS-AVP-21D9, Cyclosporine, PRX-8066, QLT091001)

  5. Pediatric over-the-counter liquids found to have variable and inconsistent dosing directions and measuring devices
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