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Formulary, A peer-reviewed drug management journal for managed care and hospital decision-makers
Part of the Modern Medicine Network

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FormularyJournal.com

July 1, 2011

Formulary
Home Medication Safety FDA Actions Latest News Policy Watch Drug Watch
In This Issue
Intensive-dose statin therapy may increase diabetes risk
FDA calls for changes in ESA dosing for patients with chronic kidney disease
New evidence-based guidelines for PDN treatment
FDA approves generic Levaquin

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With the recent introduction of 2 new protease inhibitors as adjunctive therapies for the management of hepatitis C, what do you envision your organization's approach will be to managing the use of these products?

a) Selection of 1 preferred product only

b) Maintain both agents on formulary and allow providers to choose

c) Employ prior authorization to validate clinical appropriateness before coverage

d) a & c

e) b & c

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Intensive-dose statin therapy may increase diabetes risk

Intensive-dose statin therapy appears to be associated with an increased risk of new-onset diabetes compared with moderate-dose therapy, according to a meta-analysis of data from 5 statin trials published in the June 22/29 issue of JAMA. Read full article.

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FDA calls for changes in ESA dosing for patients with chronic kidney disease

FDA has announced more conservative dosing recommendations for erythropoiesis-stimulating agents (ESAs) when they are used to treat anemia in patients with chronic kidney disease (CKD) because of the increased risks of cardiovascular events such as stroke, thrombosis, and death. Read full article.

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New evidence-based guidelines
for PDN treatment

In an effort to address the efficacy of various treatment options available to reduce pain and improve physical function and quality of life (QOL) in patients with painful diabetic neuropathy (PDN), a broad literature review was conducted and new guidelines were published online May 17 in Neurology, as well as presented at the American Academy of Neurology Annual Meeting in Honolulu. Read full article.

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FDA approves generic Levaquin

FDA approved the first generic versions of Levaquin (levofloxacin), an antibiotic approved to treat certain infections in people aged 18 and older. Read full article.

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Top 5 Web Stories

  1. A review of systemic lupus erythematosus and current treatment options

  2. FDA Pipeline Preview, May 2011 (Eli Lilly, Vertex, Regeneron Pharmaceuticals, Nile Therapeutics, Provectu

  3. FDA Actions in Brief May 2011 (Actemra, Menactra, Zytiga, Rituxan, Invega, Vandetanib, Viramune XR, Horizan

  4. PPI's efficacy and safety questioned for pediatric GERD

  5. Bazedoxifene: An investigation selective estrogen receptor modulator for the treatment and prevention of osteoporosis in postmenopausal women
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