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Formulary, A peer-reviewed drug management journal for managed care and hospital decision-makers
Part of the Modern Medicine Network

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FormularyJournal.com

September 30, 2011

Formulary
Home Medication Safety FDA Actions Latest News Policy Watch Drug Watch
In This Issue
Long-term use of nonaspirin NSAIDs may increase RCC risk
Anti-nausea drug ondansetron may lead to fatal arrhythmias: FDA
FDA approves first biologic treatment for children with ulcerative colitis
FDA panel recommends labels on bisphosphonates clarify length of use
Changes needed to pharma marketing practices
Intranasal insulin may benefit patients with aMCI and AD
NSAID use low but not rare among patients with CKD

Survey

This month we would like to know...

With the recent announcement of Medco's acquisition by Express Scripts, potentially bringing 2 of the nation's largest PBMs together, what do you see as the most significant implications of such consolidation for the industry?

a) Enhanced competition within the industry, inevitably translating to even lower drug costs for PBM payer clients.

b) Unfair advantages for Express Scripts based upon its size, thus reducing competition and potentially increasing long-term costs for payers.

c) Increased pressures on retail pharmacies forcing more pharmacies out of business.

d) Increased quality of PBM clinical, analytic and administrative services across the industry, as other PBMs strive to stay competitive.

e) Minimal, if any, impact.

Click Here to Vote

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Long-term use of nonaspirin NSAIDs may increase RCC risk

The long-term analgesic use of nonaspirin nonsteroidal anti-inflamatory drugs (NSAIDs) may increase risk of renal cell cancer (RCC), according to a study published September 12, 2011, in Archives of Internal Medicine. Read full article.

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Formulary Staff

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CONTINUING PHARMACY EDUCATION

Drug Topics and The University of Connecticut School of Pharmacy launch the next generation of learning for pharmacists

Beginning with the September issue, learn about Opioid Pain Management: Balancing Risks and Benefits. You'll earn 2 free CPE credits and enhance your skills with this valuable online benefit.

Click here for more information and to access the program.

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Anti-nausea drug ondansetron may lead to fatal arrhythmias: FDA

FDA examines the possibility that ondansetron (Zofran, GlaxoSmithKline) may lead to abnormal and potentially fatal heart arrhythmias. Read full article.

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FDA approves first biologic treatment for children with ulcerative colitis

FDA has approved infliximab (Remicade, Janssen Biotech) for the treatment of moderately to severely active ulcerative colitis in pediatric patients older than 6 years who have had an inadequate response to conventional therapy. Read full article.

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FDA panel recommends labels on bisphosphonates clarify length of use

The labeling for bisphosphonates needs to be more specific with regard to how long the drugs should be used for the treatment of osteoporosis, an advisory panel to FDA recently recommended. Read full article.

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Changes needed to pharma marketing practices

Industry-wide changes in the way pharmaceutical companies conduct marketing activities are needed, according to a recent study published September 12, 2011, in Archives of Internal Medicine. Read full article.

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Intranasal insulin may benefit patients with aMCI and AD

Intranasal insulin may have a therapeutic benefit for adults with amnestic mild cognitive impairment (aMCI) or Alzheimer’s disease (AD), according to the results of a pilot study reported online September 12, 2011, in the Archives of Neurology. Read full article.

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NSAID use low but not rare among patients with CKD

Healthcare providers should be aware of the use of nonsteroidal anti-inflamatory drugs (NSAIDs) among patients with chronic kidney disease (CKD) and may need to more clearly communicate risks and benefits, according to the results of a study reported in the September/October issue of Annals of Family Medicine. Read full article.

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