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COLUMNS
COLUMN WATCH
Stationary Phases for Modern Thin-Layer Chromatography

Fred Rabel and Joseph Sherma
Advantages of the planar, off-line format of TLC relative to on-line column HPLC, the steps in TLC analyses, and future prospects of TLC are discussed.

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Designer Drugs Analysis - Agilent Technologies online seminar series
Stay up-to-date on the latest designer drugs and integrated workflow solutions that help deliver accurate and comprehensive results. Hear from some of the leading forensic toxicology thought leaders on the latest methods for analysis. Register now to join us for all the e-Seminars in this series. Register now.

LC TROUBLESHOOTING
When Should an Internal Standard Be Used?

John W. Dolan
Will an internal standard always improve data quality?

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VICI's New Catalog
VICI Valco Instruments Co Inc introduces its new general catalog #65. The VICI catalog has been called "the bible of chromatography". Its first catalog since 2009, the VICI family presents the latest product developments as well as the full line of Valco and Cheminert® GC, LC, HPLC, and UHPLC valves, fittings, and accessories, as well as Metronics calibration devices and Precision Sampling products. There is even a glossary and handy reference section. Ask for yours today – www.vici.com or valco@vici.com. http://www.vici.com/catalog.php

MS – THE PRACTICAL ART
New Frontiers for Mass Spectrometry in Lipidomics, Part II

Giuseppe Astarita
Mass spectrometry analysis of lipids in complex matrices is revolutionizing the way lipid research is conducted.

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THE MASS SPECTROMETRY TOOL BOX
Biopharmaceutical Characterization
Live Webcast: Wednesday, June 20, 2012 at 1:00 PM EDT
Register Free at http://www.chromatographyonline.com/toolbox

INNOVATIONS IN HPLC
The Spectro–Electro Array: A Novel Approach for the Measurement of Secondary Metabolites in Botanicals, Supplements, and Beverages

P.A. Ullucci, B.A. Bailey, D.H. Thomas, and I.N. Acworth
HPLC with diode-array and electrochemical-array detection overcomes sensitivity and specificity limitations in natural products analysis.

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EDITORS' SERIES - A Roadmap for Rapid HPLC Method Development: A Practical Three-Pronged Approach
Live Webcast: Tuesday, June 26, 2012 at 11:00 am EDT
Register Free at http://www.chromatographyonline.com/rapid

THE ESSENTIALS
Performance Characteristics Measured in Method Validation

Analytical method validation is the process of demonstrating that a method does what it is intended to do.

ARTICLES
Capillary Electrophoresis–Mass Spectrometry for the Analysis of Biopharmaceuticals
Rob Haselberg, Gerhardus J. de Jong, and Govert W. Somsen
CE–MS using noncovalent coated capillaries provides advantages for purity and stability analysis of biopharmaceutical.


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