ARTICLE

Gas Chromatography with Soft Ionization Mass Spectrometry for the Characterization of Natural Products
Frank David Melissa Dunkle, Bart Tienpont, Kazuhisa Mitsui, Nobu Ochiai, Kikuo Sasamoto, Nobukazu Higashi, and Pat Sandra
The application of gas chromatography (GC) combined with atmospheric pressure chemical ionization mass spectrometry (GC–APCI_MS) and with supersonic molecular beam ionization mass spectrometry (GC–SMB-MS).

ADVERTISEMENT Advance Protein Characterization Resolve and identify critical peptides in a digest with Agilent AdvanceBio Peptide Mapping columns, specially tested with a demanding peptide mix to ensure reliable peptide mapping performance. Explore AdvanceBio columns for LC/MS and LC/UV, and take your characterization further.Get tips and advice.

COLUMNS

Column Watch
Top 10 Column Myths in Modern HPLC: Part 1
Ronald E. Majors
In any field, there are “misconceptions” or “myths” that arise and are perpetuated and passed on to the next generation. These myths are often driven by a lack of understanding of the real issues by practitioners. In the first of a two-part feature from Ron Majors, the top 10 high performance liquid chromatography (HPLC) column myths are presented and attempts are made to demystify them by offering some evidence that they are untrue. This part will feature myths 10 to six.

LC Troubleshooting
Past, Present, and Future – 30 Years of LC Troubleshooting
John W. Dolan
What’s happened in the last 30 years? What will happen next?

GC Connections
How Do Your Peaks Measure Up?
John V. Hinshaw
John Hinshaw examines the anatomy of chromatographic peaks with attention to features that help determine the suitability of individual chromatographs for a specific analysis task.

History of Chromatography
Barry Karger: Scientist, Mentor and Innovator
Howard Barth
The innovative and inspiring career of Barry Karger is described, including his pioneering work in bioanalysis.

The Essentials
Successfully Translating GC Methods from Helium to Hydrogen Carrier Gas
There are many parameters that need to be considered when considering the use of hydrogen as a carrier, however the benefits to chromatography and money saving make this a worthwhile exercise.

DEPARTMENTS:
Products
Events

The October issue will also be accompanied by a special supplement: "Recent Developments in HPLC and UHPLC"

Upcoming Webcasts

Ion Mobility – A New Beginning for Pesticide Residue Screening?

Editors’ Series: Environmental Analysis Using Ion Chromatography Coupled with ICP-MS, with Examples from Climate Change Studies

Editors’ Series: Fundamentals, Optimization and Practical Aspects of UHPLC: Series 1:  Fundamentals, Optimization and Practical Aspects of UHPLC