March 2013
  
LCGC Europe Single Sponsored Application Note Alert
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Drugs
Determination of 32 Cathinone Derivatives and Other Designer Drugs in Serum by Comprehensive LC Triple Quadrupole MS-MS Analysis
Madelenine J. Swortwood and Anthony P. DeCaprio, Department of Chemistry and Biochemistry, International Forensics Research Institute; and Diane M. Boland, Miami-Dade Medical Examiner Department of Toxicology Laboratory
There are few comprehensive screening techniques for the detection and quantification of designer drugs in biological specimens. The liquid chromatography triple quadrupole tandem mass spectrometry (LC triple quadroupole MS-MS) method encompasses compounds of designer drug classes that have been developed and validated. Read More		 Compendium: "Identification of Synthetic Cannabinoids in Herbal Incense Blends by GC–MS"
Fran Diamond, Technical Director at NMS Labs
Agilent's expanded application compendium, "Identification of Synthetic Cannabinoids in Herbal Incense Blends by GC–MS," contains information on 45 cannabinoids and describes how to facilitate rapid screening and identification of these marijuana-like compounds. Read More
 
Toxicology
Application Compendium – Analysis of Designer Drug Stimulants (Bath Salts) by GC–MS
Fran Diamond, Chemistry Technical Leader at NMS Labs
A new wave of drugs has swept through the drug community. These new compounds are chemical variations of older traditional stimulant drugs. Popularly known as "bath salts," these are dangerous compounds and have not been tested in humans. These compounds are generally basic amine compounds and can easily be extracted. Read More		 Application Compendium: Drugs of Metabolites in Oral Fluid: Immunoassay Screening and LC–MS–MS Confirmation and Quantification
James Tuyay, Cynthia Coulter, and Christine Moore, Immunalysis Corporation
Agilent Technologies has partnered with Immunalysis Corporation, a leader in oral fluid collection and screening technology, to develop the first comprehensive end-to-end workflow for the collection, preparation, screening, confirmation, and quantification of drugs in oral fluid. Read More
Raise Your Sample Filtration Standards with the New Agilent Captiva Syringe Filters
Agilent Technologies
Sample filtration prior to analysis is critical to achieving optimal system performance. Agilent Captiva Premium Syringe Filters make the process faster and easier than ever.Read More 		Determination of Cannabinoids (THC) in Biological Samples
Joe Crifasi, Saint Louis University Forensic Toxicology Lab; and Ron Honnold and Robert Kubas, Agilent Technologies
A method has been developed on the Agilent 220 Quadrupole Ion Trap using EI-MS-MS for the identification and quantification of Delta-9-THC,11-Hydroxy-THC and 11-Nor-Delta-9-THC-COOH in biological samples. Read More

Analysis of Designer Drugs "Bath Salts" by Quadrupole Ion Trap GC–MS
Ron Honnold, PhD, and Rafael Acosta, Agilent Technologies
With more sophisticated production methods and ease of obtaining designer drugs of abuse, forensic laboratories face increasing challenges. The rapid influx of cases involving designer drugs sold as "bath salts" pose a unique opportunity to develop fast analytical methods.Read More
 
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