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13 August 2015 |
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Rudolf Krska on Mycotoxin Analysis Using LC–MS–MS
Mycotoxins are an important group of secondary metabolites produced by fungi that can cause disease in humans and animals. Rudolf Krska from BOKU, IFA-Tulln in Vienna, Austria, talks about how to detect multiple mycotoxin biomarkers using LC–MS–MS and the importance of the approach in developing countries. |
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Micro-SPE Desalting With Reduced Losses |
New! Micro-volume TARGA® C18 SPE chemistries to desalt peptide, glycopeptide or glycan samples. Desalting with the water wettable, TARGA® C18 UltraMicroSpin™ columns, by loading in 100% water, improves recovery of these polar molecules prior to LCMS. Try our TARGA C18 as your desalting protocol, today! The Nest Group, Inc. - “Not Just Columns ... Answers!” Learn more |
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Photo Credit: TEK IMAGE/SCIENCE PHOTO LIBRARY/Getty Images |
Solid-Phase Microextraction in Clinical Diagnostics
Researchers at the University of Waterloo in Canada are collaborating with clinicians at Toronto General Hospital to develop preclinical and clinical applications of SPME. The Column spoke to Barbara Bojko from the team to find out more. |
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Distorted Peaks — A Case Study
LC Troubleshooting Editor John Dolan address the possible causes for distortion of the first two peaks in a chromatogram. |
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ACE UHPLC/HPLC Method Development Kits |
ACE Method Development Kits (providing up to 3 columns for the cost of a single column) are designed to maximise selectivity, offering an extremely powerful and reliable approach to UHPLC/HPLC method development. A complete range of kits is available including porous, solid-core and 300Å columns, in a wide range of formats including 0.5mm and 1.0mm i.d.s. Learn more |
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PEFTEC International Analytical Conference and Exhibition for Petroleum, Refining, and Environmental Analysis
The PEFTEC International Conference and Exhibition for Petroleum, Refining, and Environmental Analysis will be held on 18–19 November 2015 at the Antwerp Exhibition Centre, Antwerp, Belgium. PEFTEC will gather together scientists, laboratory managers, chemists, and environmental regulators from the chemical, petrochemical, and oil industries to share information, network, and learn about the latest methods, standards, and regulations for the industry. |
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Paired Ion Electrospray Ionization for Trace Anion Analysis
Over the last 10 years, LCGC Blogger Kevin Schug has pursued the development and application of MS-based methods to study noncovalent interactions. The one question that always arises is “Does the electrospray ionization (ESI) process effectively preserve the solution equilibrium, such that the measured relative ion intensities for free unbound and complex ion forms are indicative of relative solution-phase equilibrium concentrations for these species?” |
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Featured Product |
ViscoStar™ Differential Viscometer Detector
Wyatt Technology's ViscoStar™ viscometer, is an on-line chromatography detector for determining specific and intrinsic viscosities. The ViscoStar has at least 2X the signal-to-noise of any product available on the market Learn more |
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Photo Credit: Anthony Lee/Getty Images |
News: Diagnosing Diabetes Using Amino Acid Profiling of Hair
Profiling amino acids in scalp hair could aid the diagnosis of type 2 diabetes according to a new study. Researchers performed gas chromatography–mass spectrometry (GC–MS) on hair samples taken from diagnosed patients and healthy patients to show that type 2 diabetes alters the amino acid composition of hair's main building block, keratin, and that this biomarker could aid diagnosis in the clinic. |
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