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LCGC Europe - News Bulletin
 
8 October 2015

LCGC TV: Joe Glajch Part 1: Analytical Methods for Characterizing Biosimilars
Joe Glajch, a member of the LCGC Editorial Advisory Board and the director of analytical development at the biosimilars company Momenta Pharmaceuticals, talks about what is involved in characterizing a biosimilar and demonstrating comparability to a reference product.
NEW WEBINAR: ENHANCED MATRIX REMOVAL FOR FATTY SAMPLES
Are lipids weighing your samples down? Are you worried about losing analytes? This webinar will show how Bond Elut Enhanced Matrix Removal—Lipid can dramatically reduce lipid interferences while retaining analytes. EMR—Lipid fits easily into existing QuEChERS and dSPE workflows so you can analyze fatty samples faster and with more confidence.
Register today.
The LCGC Blog: An Open Inquiry Model for Science Education
According to LCGC blogger Kevin Schug, there is a shortcoming in our current educational system: too much rote learning, and not enough time given to let science-minded students explore a topic. He says that when students ask their own questions (not ones given to them by instructors), they become more invested in finding the answers.
 

Photo Credit: mustafahacalaki/Getty Images
Incognito: How Dare You! The Emotive Matter of Questioning Chromatographic Integration
Have data systems improved to the point at which we have overcome major barriers? Or have we been so brain-washed by the regulators that we must avoid reintegration (especially manual integration) at all costs, which has led to a reluctance to apply legitimate adjustments to errors created by our data systems?
Removal of Contaminant Peaks in Reversed-Phase Gradient Liquid Chromatography for Improved Detection of Pharmaceutical Impurities
The authors present a method for comparing the levels of baseline interference arising from common laboratory mobile phase contamination sources and assess different approaches for removing dissolved contaminants to generate interference free chromatogram baselines. This article demonstrates that recirculating mobile phase through a semi-preparative scale column using a reagent delivery pump to be more effective than previously published mobile phase decontamination methods.
University students and staff get 5 Years of Free Access to CHROMacademy made possible by Agilent Technologies- the world’s premiere measurement company. Learn More
Technical Tip: Static Headspace Sampling
Static headspace sampling is typically used for the determination of volatile and semi-volatile analytes in liquids and, more rarely, solid matrices. Application examples include the analysis of alcohols in blood, residual solvents in pharmaceuticals, flavours and taints in food and beverages as well as fragrances in perfumes and detergents.
Featured Products
New Restek® Rxi®-1301Sil MS GC Columns Are Ideal for MS The First SEC-MALS detector for UHPLC TSKgel Amide-80 for UHPLC
Restek's Rxi®-1301Sil MS GC columns give you the selectivity you need without the bleed. These new columns offer true cyano phase selectivity along with the highest thermal stability in the industry, which ensures you get dependable, accurate MS results and increased uptime. Improve the performance of existing methods for solvents, glycols, and other polar compounds with an Rxi®-1301Sil MS GC column. Learn more The µDAWN™ is the world's first multi-angle light scattering (MALS) detector that can be coupled to any UHPLC system in order to determine absolute molecular weights and sizes of polymers, peptides, and proteins. Learn more TSKgel Amide-80 is now available in 2 micron particle size. For years, TSKgel Amide-80 columns are used successfully for HILIC separations of polar compounds such as saccharides, glycans, oligosaccharides, or peptides. The amide chemistry is particularly popular for glycosylation analysis of proteins. The new small particle size columns deliver higher resolution and peak capacity and are ideally suited for UHPLC and UHPLC-MS. Learn more
 
 
Upcoming Webcasts

Overview of Hydrophilic Interaction Chromatography (HILIC)
Tuesday, October 20, 2015
2:00—3:00 pm EDT

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Understanding the Impact of System Dispersion on Separation Performance
Tuesday, October 27, 2015
8 am EDT/ 11 am EDT/ 3 pm GMT/ 4 pm CET

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Streamlining Routine Workflows in the Environmental Laboratory
Wednesday, October 28, 2015
11 am EDT/ 8 am PDT/ 3 pm GMT/ 4 pm CET

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On Demand Webcasts
Streamlining Routine Workflows in the Environmental Laboratory, Part I
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Accelerating HPLC/UHPLC Method Development Strategies by Leveraging Selectivity: Influence of Unique C18-Based Stationary Phases
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The Utilization of LC–MS–MS in Development of Solid-Phase Extraction Methods
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Characterization of Prebiotics Using High-Performance Anion Exchange Chromatography (HPAEC) at High pH Coupled with Pulsed Electrochemical Detection (PED)
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