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LCGC Europe - News Bulletin
 
20 November 2015

LCGC TV: Advancing Chromatographic Methods
Kate Rimmer of the National Institute of Standards and Technology (NIST) discusses separation science research carried out at NIST — on using 2D LC to quantitate polycyclic aromatic hydrocarbons, the challenges of identifying the best peak integration approach, and where 2D LC research is heading next.
The LCGC Blog: GC Troubleshooting in 20 Pictures (Part 1)
This month Tony Taylor has taken inspiration from a recent webcast, presented at www.chromacademy.com, in which he presented real data from their work that represents some “classic” GC problems.
 

Photo Credit: Dr. Roman Labuda
Multi-Toxin Determination in Food – The Power of “Dilute and Shoot”
This article provides useful tips for smooth validation of multi-analyte LC–MS–MS methods in food analysis.
 

Photo Credit: PASIEKA/Getty Images
Changing from Helium and Nitrogen While Maintaining Separation Efficiency and Analysis Time
Most scientists in the world of gas chromatography (GC) will advise you not to use nitrogen because it is considered a “dinosaur” gas, and instead use helium, which offers shorter analysis time. But, wouldn’t it be very nice if we could make nitrogen work for applications where helium is not an option?
 

Photo Credit: Rafe Swan/Getty Images
Meeting Review: Advances in Bio-Separations: Biologics Characterization from Cradle to Grave (Day One)
The first of a two-part review of the Advances in Bio-Separations meeting, organized by The Chromatographic Society. Focusing on the characterization of biopharmaceutical molecules at AstraZeneca’s MedImmune site in Cambridge, UK, the programme covered the analysis of peptides, oligonucleotides, and monoclonal antibodies (mAbs), proposing multiple approaches towards the successful analysis of these types of molecules.
 

Photo Credit: GIPhotoStock/Getty Images
GC–MS of Breast Cancer Cell Lines
Gas chromatography–mass spectrometry (GC–MS) could be used to aid the characterization of breast cancer cells according to a new study published in the journal Scientific Reports. The study authors report that the levels of 13 volatile organic compounds (VOCs) in the headspace above breast cancer cell lines varied in vitro and were indicative of different disease markers including stage of development, receptor expression, and doubling time.
 
 
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