LCGC Europe Weekly Update:
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LCGC Europe - News Bulletin
 
16 December 2015

LCGC TV: Joe Glajch Part 3: Strategies for Demonstrating Similarity of Biologics
Joe Glajch, a member of the LCGC Editorial Advisory Board and the director of analytical development at the biosimilars company Momenta Pharmaceuticals, discusses how fully a biopharmaceutical can be characterized. He also talks about the role of statistical approaches in determining the acceptance criteria for biosimilars.
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The LCGC Blog: In Defense of Nitrogen as a Carrier for Capillary GC
In the latest instalment of the LCGC Blog, a simple case study is presented that highlights how to use nitrogen as a replacement for helium.
 
 
The New Agilent 5977B GC/MSD
Agilent 5977B GC/MSD with High Efficiency Ion Source (HES) gives you 10x improvement in capabilities. This revolutionary single-quadrupole GC/MS, offers two distinct advantages: 10x greater sensitivity (detection limits as low as 1.5fg IDL) and 10x less sample required- now spend less time performing sample prep and maintenance, while saving on shipping costs at the same time. Learn more now!
 
Hamish Small: Experimenter Extraordinaire
Hamish Small spoke to André Striegel about the secrets to his success in separation science and the value of vague thoughts in scientific progress.
 
Featured Application Note
Triglycerides in Vegetable Oils using Gas Chromatography
Fats and oils are parts of normal daily consumptions and are considered as important nutrients in human diets. Almost all of commercially fats and oils of animal or plant origin consist of the lipid class called triglycerides (or triacylglycerols). GC is one of the most employed analytical techniques for analyzing lipid and fatty acids content of vegetable oils. Here are reported profiles of different vegetable oils triglycerides analysis, using efficient short MEGA-SE52 GC column; the use of shorter columns with Cold On-Column injection type allows to minimize the thermal degradation of these compounds thus permitting a correct quantification. Read more
 

Photo Credit: elly99/Getty Images		 Split Injection GC: The Benefits of “Shoot-and-Dilute” GC
Jack Cochran’s new column “Practical GC” aims to provide readers with practical advice on how to get the best results from their gas chromatography (GC) systems. The first article in a series on split injection GC focuses on the advantages of using “shoot-and-dilute” GC.
 

Photo Credit: Alessandro Di Noia/Getty Images		 News: Analyzing Edvard Munch
Researchers from the University of Pisa, Italy, have devised a new method to characterize complex oil mixtures in paintings using high performance liquid chromatography–electrospray ionization-quadrupole-time of flight mass spectrometry (HPLC–ESI-QTOF-MS).
 
Featured Products
Wyatt TSKgel Size Exclusion Columns for UHPLC
The µDAWN™ is the world's first multi-angle light scattering (MALS) detector that can be coupled to any UHPLC system in order to determine absolute molecular weights and sizes of polymers, peptides, and proteins.
Learn more 		TSKgel UP-SW3000 columns packed with 2 µm silica based particles are the latest addition to the popular TSKgel SW series, the gold standard for QC analysis of antibody therapeutics. The new silica-based UHPLC columns are based on the proven proprietary surface technology of the TSKgel SW family and are ideally suited to facilitate the transfer of existing HPLC methods to UHPLC systems.
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The Cannabis Analytical Conundrum: A Discussion of Analytical Requirements and Method Development
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