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In our August issue:
COLUMNS
LC TROUBLESHOOTING
Ultraviolet Detectors
Detectors based on ultraviolet absorbance are the most common detectors in use for liquid chromatography. John Dolan explains more.
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SAMPLE PREPARATION PERSPECTIVES
Sample Sizes
This month Doug Raynie takes a quick look at the role of sample homogeneity and the determination of sample size.
PERSPECTIVES IN MODERN HPLC
Quality Control in Drug Development
This fourth and last instalment in the “Separation Science in Drug Development” series provides an overview of modern practices of quality control in small-molecule drug development.
PEER-REVIEWED ARTICLES
Advanced Systematic Toxicological Analysis
Systematic toxicological analysis (STA) is an important step in medicolegal investigations of death, poisoning, and drug use. The primary goal of such analysis is the detection and confirmation of potentially toxic compounds in evidence. This article describes a workflow employing non-targeted liquid chromatography/tandem mass spectrometry (LC–MS/MS) for reliable compound identification.

Improved Sensitivity and Specificity for trans-Resveratrol in Red Wine Analysis with HPLC–UV and LC–MS
Adequate detection of trans-resveratrol in wine is complicated by two factors: relatively low levels and interferences from matrix components. Here, we present two useful approaches for overcoming these challenges.
UPCOMING WEBCASTS

Using the X500R QTOF with SWATH Acquisition for Confident Contaminant (PFAS), Flavor, and Color Analysis: Screen, Quantify, & Identify Unknowns
Tuesday, August 16, 2016
11 am EDT | 10 am CDT | 8 am PDT
Register here>>

Analytical Workflow Tools for Monoclonal Antibody Development and Characterization
Wednesday, August 24, 2016
2:00 pm EDT
Register here>>

Extreme-Throughput, Comprehensive Gas and Headspace Analysis: Automated SIFT-MS
Thursday, August 25, 2016
8 am PDT | 11 am EDT | 4 pm BST | 5 pm CEST
Register here>>

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Pesticide Testing
Pesticide Testing

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