Phase Extraction System for Perfluorinated Compounds in Water
This application note addresses the concern over the levels of perfluorinated and polyfluorinated chemicals in the environment, their fate and possible adverse effects.

Determination of Beta-Blockers in Urine Using SFC/MS
This Application Note demonstrates the separation and quantification of beta-blockers, listed as prohibited substances by the World Anti-Doping Agency, in urine using the Agilent 1260 Infinity Analytical SFC System.

Fast, High-Resolution Size Exclusion Chromatography of Aggregates in Biotherapeutics
This application note describes techniques to increase sample throughput without compromising the accuracy of analysis during the monitoring of aggregate formation during biotherapeutic development.

UHPLC Glycosylation Analysis of Protein Therapeutics
Characterization of glycosylation is a major quality parameter in the production of biotherapeutics.  This note demonstrates the benefits of using a new, small particle TSKgel Amide-80 HILIC column which improves peak capacity and sensitivity for UHPLC and LC-MS analysis of labelled glycans.

Absolute Molar Mass in UHPLC via the µDAWN and UT-rEX
Ultrahigh-performance liquid chromatography (UHPLC) enables fast, efficient separation of biomolecular samples. Compared to standard SEC, UHPLC–SEC provides improved resolution, higher throughput, less solvent, and smaller sample consumption for analysis of precious biological samples.

Ultra-Sensitive 1,25 di-OH Vitamins D2/D3 Determination Using ISOLUTE SLE+
This application note describes the use of ISOLUTE SLE+ for extraction of 1,25 di-OH Vitamins D2 and D3 metabolites from serum. Sensitivity is maximized by use of a simple PTAD derivatization and formation of a methylamine complex prior to LC-MS/MS analysis.

A New PEG GC Column with Improved Inertness Reliability and Column Lifetime
WAX type columns are the industry standard, analyzing a wide range of compounds with polar functional groups. The new Agilent DB-WAX Ultra Inert GC column is presented.