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Sample Prep Automated Low Background Solid Phase Extraction System for Perfluorinated Compounds in Water There has been increasing concern over the levels of perfluorinated and polyfluorinated chemicals, such as PFOS and PFOA, in the environment and possible adverse effects. ...Read more   Hyphenated EPA Method 544: Determination of Microcystins and Nodularin in Drinking Water by SPE and LC–MS-MS Detection Microcystins are a group of hepatotoxins produced by freshwater cyanobacteria (also known as blue-green algae). Microcystins can be generated in large quantities during algae blooms ...Read more The Big Pain: Development of Pain-Free Methods for Analyzing 231 Multiclass Drugs and Metabolites by LC–MS-MS As the demand for testing of pain management drugs increases, many laboratories are turning to LC–MS-MS for its increased speed, sensitivity, and specificity. The ...Read more   General Qualitative Pesticide Screening High-resolution mass spectrometry techniques are essential for monitoring food and environmental samples across the globe; they can monitor unlimited targets at the same time as discovering ...Read more IEX Method Transfer This application note demonstrates a complete SFE-SFC workflow solution using an MV-10 ASFE System (MV-10) and a Prep 80q SFC System for the extraction and ...Read more Purification of Vanillin Using an SFE-SFC Workflow This application note demonstrates a complete SFE-SFC workflow solution using an MV-10 ASFE System (MV-10) and a Prep 80q SFC System for the extraction and ...Read more High-Speed Process Monitoring with UHP-SEC-MALS Size-exclusion chromatography (SEC) is widely used for detecting aggregates, fragments, and other impurities in a biotherapeutic sample. When coupled with multi-angle light scattering, SEC enables ...Read more   HPLC Analysis of Polycyclic Aromatic Hydrocarbons by 2D-LC PAHs were determined in a petroleum vacuum distillation residue using the Agilent 1290 Infinity Multiple Heart-Cutting 2D-LC solution with normal-phase in the first dimension and ...Read more Use of 1.9 µm YMC-Triart C18 and 2.7 µm YMC Meteoric Core C18 BIO Stationary Phases for Fast Peptide Mapping of Monoclonal Antibodies Improvements in speed, resolution, and solvent consumption are offered by sub-2 ?m totally porous and superficially porous core-shell stationary phases when used for peptide mapping ...Read more The Advantages of Using Multimode Column in Separation of Ascorbic Acid and Its Derivatives Ascorbic acid and its derivatives were successfully retained and separated on Scherzo SM-C18 multimode columns. Presented results highlight the advantages of utilizing multiple retention mechanisms ...Read more Routine Multiresidue Pesticide Analysis Using the Agilent 6470 Triple Quadrupole Mass Spectrometer This application note describes a UHPLC–MS–MS-based method for the screening and quantification of more than 250 pesticides and pesticide metabolites in food samples. ...Read more Fast Determination of the Bitter and Clove-Like Flavor in Beer with the Agilent 1290 Infinity II LC In this application, the Agilent 1290 Infinity II LC was used to determine the bitter compounds iso-alpha-acids and reduced iso-alpha-acids, and the clove-like phenolic flavor ...Read more DAR Analysis of Antibody Drug Conjugates In this application note, an ADC was separated using a TSKgel Butyl-NPR column, the least hydrophobic of the TSKgel HIC columns. Both unconjugated and drug conjugated Trastuzumab samples were successfully ...Read more Sample Prep for Sensitive HPLC Detectors The Samplicity® filtration system was developed to filter up to eight samples directly into standard high performance liquid chromatography (HPLC) vials using vacuum-based filtration. The samples can then be used ...Read more   Application Note Library Subscribe to the Application Note Alert LCGC Print Edition LCGC Digital Edition