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The Challenge of Accurate Protein Bioanalysis

In recent years, liquid chromatography–tandem mass spectrometry (LC–MS-MS) methods have been increasingly adopted as a replacement for ligand-binding assays to monitor the fate of drugs in vivo. Such bioanalysis of protein-based pharmaceuticals (biopharmaceuticals) is more challenging, however, than it is for small-molecule drugs. Rainer Bischoff of the University of Groningen in the Netherlands has been exploring approaches to overcome these challenges. He recently spoke to us about this work. read more

Join us for an exciting journey and find out how to increase analytical confidence in biopharmaceutical peptide mapping. This LIVE four-part series focuses on optimizing each step within a peptide mapping workflow. Several powerful, new technologies will be discussed that address and improve upon slower, less-reliable and highly variable methods currently used to examine biotherapeutics. The fastest route to outstanding reproducibility. Upgrade your maps! Register NOW