LCGC Europe - Weekly Update

LCGC Europe Weekly Update:
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10 March 2016

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Characterizing Biological Processes in Single Cells Using Capillary Electrophoresis
The characterization of transcripts, proteins, peptides, and metabolites in cells is important to study disease mechanisms and develop novel therapeutics. Peter Nemes of George Washington University, Washington, USA, spoke to The Column about the important role of CE–ESI and TOF-MS in this area of research.

Solve your GC Pain Points

As regulatory agencies drive LODs lower for active analytes, you cannot afford adsorption caused by flow path activity. For starters, active GC flow path surfaces can cause peak tailing and signal loss, preventing sensitive analytes from being detected. What's more, repeating or re-verifying suspect analyses wastes resources, hinders productivity and hurts your bottom line.

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A Stoichiometric Displacement Model for Proteins in Reversed-Phase LC
The literature on reversed-phase liquid chromatography of proteins is reasonably well developed, but not taught in the college classroom to a significant degree. So I would like to focus on a stoichiometric displacement model for reversed-phase LC of proteins that I found to be particularly insightful from a practical standpoint.

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LCGC TV: Testing the Performance of Ionic Liquid Coatings for SPME
The selectivity of an ionic liquid coating is of the utmost importance for an application. Jared Anderson from the Iowa State University discusses the results achieved when testing the coatings in the analysis of PCBs and volatile compounds in cheese.

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Leading Light: Pavel Jandera
Pavel Jandera spoke to Frantisek Foret about building his own liquid chromatograph, the birth of “modern” HPLC, the importance of exploring (and understanding) earlier research papers, current trends in contemporary chromatography, and offers inspiring advice for aspiring chromatographers.

Mechanisms of Interaction Responsible for Alternative Selectivity of Fluorinated Stationary Phases
In this instalment of “Column Watch”, the differences between alkyl phases and PFP phases are discussed in terms of fundamental interactions. The origin of the interactions is also interpreted to better understand how analysts can use and control them to develop effective and rugged analytical methods.

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Upcoming Webcast

Reporting on Chromatographic Data Doesn't Have to be Painful
Tuesday, April 5, 2016
8 am PDT / 10 am CDT /11 am EDT /4 pm BST / 5 pm CEST
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On Demand Webcasts

Pesticide Residue Analysis Webinar: Utilizing the Power of GC-Orbitrap MS Technology for the Multi-Residue Analysis of Pesticides
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Fast, Cost-Effective IC Methods for Testing Environmental Waters
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Development Partners for BioPharma: Are You Getting What You Need?
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Data Integrity in Pharma QC Labs: What you Need to Know
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What Every Pesticide Analyst Needs to Know: Expert Roundtable Discussion
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