In our June issue:
COLUMNS
LC TROUBLESHOOTING
USP Method Adjustment
When you want to adjust a USP method for a different size column or to meet system suitability criteria that fail, how much of a change can you make without revalidating the method? Read more >> |
SAMPLE PREPARATION PERSPECTIVES
Sample Prep Products Review
This yearly report on new products introduced at Pittcon (or in the preceding year) covers sample preparation products.
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PERSPECTIVES IN MODERN HPLC
Perspectives and Instrumental Features in UHPLC
Historical perspectives on the development of ultrahigh-pressure liquid chromatography (UHPLC) into a modern high performance liquid chromatography (HPLC) platform are highlighted and the important instrumental features common to most commercial equipment are discussed. Read more >>
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COLUMN WATCH
Retention Mechanisms of Biphenyl Stationary Phases
Retention mechanisms of biphenyl phases are investigated and contrasted to more common alkyl phases. Read more >>
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PEER-REVIEWED ARTICLE
On The Fast Track
Some 50 years after Giddings’s iconic comparison of the separation speed of GC and LC, this article revisits this comparison using kinetic plots of the current state-of-the-art systems in LC, SFC, and GC. It is found that, despite the major progress LC has made in the past decade (sub-2-µm particles, pressures up to 1500 bar, core–shell particles), a fully optimized UHPLC separation is still at least one order of magnitude slower than capillary GC. The speed limits of packed bed SFC are situated in between.
Read more >> |
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| The Recent Developments in HPLC and UHPLC Supplement is also featured alongside LCGC Europe's June issue. |
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