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HPLC 2017 Topic Preview

The Role of LC–MS in Lipidomics

Gerhard Liebisch discusses the role that liquid chromatography–mass spectrometry (LC–MS) plays in lipidomics. This is the sixth in a series of articles exploring current topics in separation science that will be addressed at the HPLC 2017 conference in Prague, Czech Republic, from 18–22 June. read more


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Enter to Win & Save on Charge Variants Profiling Kits

Understanding charge variance of biopharmaceuticals or biosimilars is critical to ensure drug efficacy and safety. We've made this process easier and faster for you with our patented Thermo Scientific CX-1 pH Gradient Buffer Kits. Enter our competition to win a kit AND get a discount!


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LCGC Blog

The LCGC Blog: Getting the Best Repeatability from Your Quantitative Gas Chromatography

I'm often asked "what reproducibility should I expect to get from my [insert instrument manufacturer and model]?" So, most folks are referring to the repeatability aspects of precision, as in: "what relative standard deviation (usually expressed at %RSD) for peak area or quantitative result should I be able to achieve from repeat injections from a single vial of sample?" read more


LCGC TV

Peter Schoenmakers on Combining Space-Based and Time-Based Separations and 3D LC: Is It Practical?

Space-based and time-based separations are often a preferred approach. Peter Schoenmakers from the University of Amsterdam discusses how they can be combined and the benefits of this approach. He also discusses the complexities of 3D LC. read more


News

Investigating Microalgae Using GC and HPLC–MS

Researchers from the Technical University of Denmark (DTC) have used gas chromatography (GC) and high performance liquid chromatography–mass spectrometry (HPLC–MS) to investigate microalgae biomass as an alternative resource for fishmeal and fish oil in the production of fish feed. read more

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Sugar Phosphates, Kreb's Acids, metabolites ...

The HILICON® iHILIC® Fusion chemistries in both column and SPE formats, address more and more polar molecule isolation challenges. Desalting with TARGA® C18, BioPureSPN™ SPE from 100% water will improve recovery of these polar molecules prior to LCMS. Try one of our Fusion or TARGA separation approaches today! The Nest Group, Inc. - "Not Just Columns ... Answers!"


HPLC 2017 Topic Preview

Affinity Capillary Electrophoresis–A Powerful Tool to Investigate Biomolecular Interactions

Václav Kašička discusses how affinity capillary electrophoresis (ACE) is a special separation mode for bioactive compounds. This is the final instalment in a series of articles exploring current topics in separation science that will be addressed at the HPLC 2017 conference in Prague, Czech Republic, from 18–22 June. read more


LC Troubleshooting

Increasing Resolution by Increasing Retention

How to find the "sweet spot" in terms of retention for a liquid chromatographic separation as well as how much retention change can be expected for a selected change in organic mobile-phase percentage or column temperature. read more


Application NoteS

Analysis of Neonicotinoids in Honey by QuEChERS and UHPLC-MS/MS

Neonicotinoids are a relatively new class of insecticide that were introduced as an alternative to organophosphate, carbamate and pyrethroid insecticides. Their novel mode of action... Read more

Use of Agilent Poroshell HPH-C18 Columns at Elevated pH as a Tool for Method Development

Chromatographers can maximize flexibility in their method development and analysis by adjusting selectivity without sacrificing column lifetime. Read more


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UPCOMING WEBCASTS

The Application of Spectral Accuracy to Mass Spectrometry for Enhanced Formula ID and Mixture Analysis

Tuesday, June 13, 2017
11 am EDT | 8 am PDT | 4 pm BST | 5 pm CEST
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Using Magnetic Sector GC–HRMS in a Commercial Dioxin Lab

Wednesday, June 14, 2017
11 am EDT | 8 am PDT | 4 pm BST | 5 pm CEST
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Who Cares about SVOCs? The Next Generation of Product Emission Testing for Indoor Exposure Modeling

Friday, June 16, 2017
11 am EDT | 8 am PDT | 4 pm BST | 5 pm CEST
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How to Understand Measurement Uncertainty in TOF Mass Spectrometry and Ion Mobility-Mass Spectrometry

Wednesday, June 21, 2017
11 am EDT | 8 am PDT | 4 pm BST | 5 pm CEST
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Complete Structural Insight into Therapeutic Proteins: Using Mass Spectrometry Under Native & Denaturing Conditions
Part I: Simplified Mass Spectral Characterization of Complex Biotherapeutic Drugs Under Native and Denaturing Conditions

Wednesday, June 28, 2017
11 am EDT | 8 am PDT | 4 pm BST | 5 pm CEST
Register>>

ON DEMAND WEBCASTS

Authenticating Botanicals and Herbal Supplements Using UPLC-QToF-MS and a Metabolomics Approach


Editors’ Series: Sample Preparation: The Forgotten Dimension in HPLC


Characterization of Substances in Food Packaging Migration Studies using LC- and GC- coupled to High Resolution Accurate Mass (HRAM) Mass Spectrometry


Chromatographic Testing in a Regulated Environment: How Can You Qualify Your Results from Pharmacopeial Monograph Methods?


NISTmAb Characterization: Purity, Charge Heterogeneity and Glycan Analyses on a Single Analytical Platform


Automated LC Method Development - Software


Recent Advances and Applications of Gas Chromatography–Vacuum Ultraviolet Spectroscopy


A Risk-Based Approach to Reviewing Electronic Chromatographic Data and Audit Trails with Data Integrity in Mind

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