LCGC Europe Application Note Alert
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CE-MS

Biosimilarity Assessment of Therapeutic MAbs by CESI-MS
In this tech note, CESI-MS was used to characterize and compare a marketed reference mAb with biosimilar candidates. A single injection of each digested mAb ...Read more

Structural Characterization of ADCs by CESI-MS
In this tech note, CESI-MS protocols for the structural characterization of ADC molecules were developed. Several ADC properties could be confirmed including:
    •   DAR ratio
...Read more


GPC

Polymer Branching Characterized by SEC-MALS
Branching affects important mechanical, rheological, and thermal properties of polymers. Quantitative information about branching topology is vital for developing novel polymer-based materials and for understanding ...Read more

 
HPLC

Analysis of Tryptic Digests of a mAb and an ADC with the Agilent 1290 Infinity II LC
High peak capacities for the analysis of Herceptin and Kadcyla tryptic digests can be achieved when using the Agilent 1290 Infinity II LC with an ...Read more

 
GC

Troubleshooting your GC and Detector with Agilent’s ADM Flow Meter
The ADM Flow meter with replaceable calibration cartridge, is an integral part of gas chromatography that can be used to verify proper function or troubleshoot a GC ...Read more

Comprehensive Analysis of Coffee Bean Extracts by GC×GC–TOF MS
This study shows that GC×GC and time-of-flight mass spectrometry provides a high-performance solution for screening complex coffee extracts for key aroma compounds. Features illustrated are ...Read more

 
Sample Prep

Solid-Phase Extraction for the Analysis of Drugs of Abuse in Urine
Many drugs of abuse (DOA) — whether natural or synthetic — are rapidly excreted from the human body. However, some can persist for extended periods. Screening for ...Read more

 
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