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The Column
April 20, 2017
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TOP STORY

Ultrafast Gas Chromatography: Key Considerations in Method Development

This article describes the principles and practical uses of ultrafast GC and the key considerations in method development using this technique. read more


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Fast, Reproducible Pesticide Residue Analysis in minutes

Traditional techniques used to perform the extraction of pesticides from food matrices are time consuming, solvent intensive and can deliver inconsistent results. The need for economical, fast, reproducible testing protocols exists. Product pesticide analysis is an area of major concern for both quality control and consumer safety. The consistent extraction of pesticides for analytical quantitation is critical. The PLE® can dramatically improve reproducibility of results, speed and cost of extractions. Application Note

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LCGC TV

LCGC TV: Alain Beck on Native MS and Ion-Mobility MS in Antibody Analysis

Alain Beck from the Center of Immunology Pierre Fabre discusses the role of native mass spectrometry in the characterization of antibody-drug conjugates and bispecific antibodies. He also discusses the benefits of ion-mobility MS in these analyses. read more


FEATURES

Dynamic Duo

Can combining stir-bar sorptive extraction (SBSE) with molecularly imprinted polymers (MIPs) extend the practical applications of SBSE? The Column spoke to Antonio Martin-Esteban of the Department of Environment of the National Institute of Research and Technology in Agricultural and Food Science (INIA) in Madrid, Spain, to find out more. read more


Tips & Tricks GPC/SEC: Quantify and Get More Than Molar Mass Averages

GPC/SEC is used to determine molar mass averages and the complete molar mass distribution with just one injection. This is possible because GPC/SEC is a fractionating technique, allowing the higher molar mass fraction to be characterized and more about low molar mass compounds such as oligomers, additives, or residual educts to be learned. read more

Application Notes

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Analysis of Tryptic Digests of a mAb and an ADC with the Agilent 1290 Infinity II LC

High peak capacities for the analysis of Herceptin and Kadcyla tryptic digests can be achieved when using the Agilent 1290 Infinity II LC with an Agilent AdvanceBio Peptide Map column. Learn more


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Troubleshooting your GC and Detector with Agilent's ADM Flow Meter

The ADM Flow meter with replaceable calibration cartridge, is an integral part of gas chromatography that can be used to verify proper function or troubleshoot a GC. Learn more


INCOGNITO

Highly Experienced Method Developer - Really?

Many applicants for method development jobs make claims they are not prepared to substantiate, either in a CV or during the interview. Here is what you should be ready to explain, or show, about your expertise and experience. read more


NEWS

Identifying Greek Drug Consumption Using LC–MS/MS

Researchers from the National and Kapodistrian University of Athens have used liquid chromatography with tandem mass spectrometry (LC–MS/MS) to understand changes in licit and illicit drug consumption patterns following the major socioeconomic changes Greece has experienced. read more


FEATURED PRODUCTS

ViscoStar III - On-line Viscometry

The ViscoStar III's sensitivity, dynamic range, resolution and stability surpass other GPC viscometers by at least an order of magnitude—all while retaining robustness, ease-of-use and serviceability. / Learn more /

YMC UHPLC Size Exclusion Columns!

For fast SEC analysis YMC introduced YMC-Pack Diol UHPLC SEC Columns. Increased throughput and improved resolution is provided with excellent reproducibility and long-term stability at the same time. / Learn more /

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