In our February issue: COLUMNS: LC TROUBLESHOOTING How Pure is Your Peak?
Is that peak "pure"? How do I know if there might be something hiding under there? Read more >>
PHARMACEUTICAL PERSPECTIVES A Look at SOS-LC
In the inaugural instalment of "Pharmaceutical Perspectives", current possibilities, pharmaceutical applications, a downloadable algorithm, and weaknesses of SOS-LC are discussed. Read more >>
COLUMN WATCH The Science Behind Packing Materials
This work demonstrates that the next generation of packing methods to be developed towards the ultimate performance of the infinite diameter column will eliminate the unevenness of the stress applied to the packed particles across the column diameter during bed consolidation.
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FEATURES Rapid Trace Analysis of Multiresidue Contaminants
Mira Petrovic from the Catalan Institute for Water Research (ICRA) in Girona, Spain, reveals the advantages and practical applications of a novel method she developed for the multiresidue trace analysis of pharmaceutical compounds and their corresponding metabolites and transformation products using dual-column liquid chromatography (LC) coupled to tandem mass spectrometry (MS/MS). Read more >>
PEER-REVIEWED ARTICLE: Biomimetic Chromatography: Part 1
In the first part of this two-part series the author describes the importance of high performance liquid chromatography-based measurements of lipophilicity and biomimetic properties in the drug discovery process. Read more >>