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In our March issue:
COLUMNS:
LC TROUBLESHOOTING
Eluent Preparation for HILIC
When preparing buffers for HILIC separations, is the buffer concentration considered relative to the aqueous portion of the eluent only, or to the aqueous–organic mixture? Read more >>
BIOPHARMACEUTICAL PERSPECTIVES
Peptide Mapping Using Micro-Pillar Array Columns
This article reports on the use of micro-pillar array columns for peptide mapping of monoclonal antibodies and antibody–drug conjugates. Read more >>
GC CONNECTIONS
The Past and Present of GC Detection
This instalment of "GC Connections" reviews GC detectors, both past and vanished, as well as current and relevant to today's separation challenges. Read more >>

PEER-REVIEWED ARTICLE:
Digital Method Development
Chromatographic principles and best practices for obtaining highly precise retention time, peak width, and resolution predictions for the optimization of reversed-phase LC separations using commercially available retention modelling software is discussed. Read more >>

The Analytica Companion is also featured alongside LCGC Europe's March issue.

UPCOMING WEBCASTS

Monitoring Volatile Organic Compounds Using GC and GC-MS: Meeting the Challenge of Protecting the 981-Mile Ohio River
Tuesday, 20 March, 2018
11 am EDT | 8 am PDT | 1500 GMT | 1600 CET
Register >>

The CHROMacademy Essential Guide to: Top Tips to Improve Reproducibility and Sensitivity in Solid Phase Extraction
Thursday, 22 March, 2018
11 am EDT | 8 am PST | 1500 GMT | 1600 CET
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Data Integrity Concerns: Challenging Chromatographic Analyses
Tuesday, 27 March, 2018
10 am EDT | 1500 BST | 1600 CEST
Register >>

Better Living Through (Flavor) Chemistry: Vacuum Ultraviolet Spectroscopy as a New Tool for GC Analysis of Terpenes in Flavors and Fragrances
Wednesday, 28 March, 2018
11 am EDT | 8 am PDT | 1600 BST | 1700 CEST
Register >>

Sensitive Forensic Screening for Drugs of Abuse in Human Urine Using Single Quadrupole GC-MS and a Simple Solid Phase Extraction
Thursday, 29 March, 2018
8 am EDT | 1300 BST | 1400 CEST
Register >>

New USP <1058> Analytical Instrument Qualification Regulations: What the 2017 Requirements Mean and How to Comply
Europe: Wednesday, 4 April, 2018 | 0900 BST | 10000 CEST
North America: Wednesday, April 4, 2018 | 1 pm EDT | 12 pm CDT | 10 am PDT
Asia Pacific: Thursday, 5 April, 2018 | 0800 IST | 1030 CST | 1130 JST
Register >>

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issues:
LCGC Europe Cover
LCGC Europe Cover

If you would like to submit an article to LCGC, contact Alasdair Matheson, Editor-in-Chief - alasdair.matheson@ubm.com.

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