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LCGC ASIA PACIFIC, News Update
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October 25, 2018

The LCGC Blog: Improve Sensitivity and Reproducibility Using Pulsed Pressure Splitless GC Injection

In my previous blog, I discussed the possibility of backflash in splitless GC injection and its effect on quantitative reproducibility and carry-over. While much is written in the literature on optimization of splitless injection conditions, little is available on the implementation and optimization of increased head pressure (pressure pulsed) injection, so we will concentrate on this aspect of injection optimization. Read more

CASSS' CMC Strategy Forum Japan is 3-4 December 2018 in Tokyo

CMC Japan will focus on topics relevant for Japan and Asia and feature presentations from PMDA (Japan), MFDS (Korea), CFDA (China), US FDA and the EMA. The meeting will have the strong support of the Pharmaceuticals and Medical Devices Agency (PMDA, Japan) and the Japan Pharmaceutical Manufacturers Association (JPMA). For more information, click here.

Py-GC–MS Analysis of Japanese Jõmon Period Lacquerware

Analysis of red lacquerwares from the Japanese Jőmon Period (approximately 14,000 to 500 BC) by pyrolysis gas chromatography–mass spectrometry (Py-GC–MS) has revealed the materials and fabrication techniques used in their production. Read more

Tips, Tricks, and Troubleshooting for Separations of Biomolecules, Part 2: Contemporary Separations of Proteins by Size-Exclusion Chromatography

Several new materials and columns have been introduced in recent years for size-exclusion separations of proteins. How do I know which one to choose, and which separation conditions will be the best for my protein separation? Read more

Safely Delivering the Best Possible Carrier and Detector Gases to Your GC System

The quality of a gas chromatogram depends heavily on the quality of the separation and detection gases, among many other factors. In this month's instalment, "GC Connections" discusses ways in which chromatographers can ensure a safe working environment while delivering gases that are up to the requirements of the separations at hand, in the context of moving a laboratory to a new location. Read more

Analytical Life Cycle Management– The Coming Revolution

Incognito looks to a coming paradigm shift and the storm of three letter acronyms set to radically update the way in which analytical methods are developed, validated, and verified. Read more

FEATURED PRODUCTS

Analysis of Phospholipids with iHILIC^®-Fusion

HILICON HILIC columns, iHILIC®-Fusion, iHILIC®-Fusion(+), and iHILIC®-Fusion(P), are versatile for the LC–MS analysis of polar compounds in "Omics" researches, pharmaceutical discovery, and clinical diagnostics. A recent application shows 10 phospholipids (PLs) classes can be well separated by an iHILIC®-Fusion column. The method is applicable for the potential clinical applications. Learn more

Separation & Characterization of Complex Charged Molecules with Electrical Field-Flow Fractionation.

Postnova presents an innovative new simultaneous Electrical and Asymmetrical Flow Field-Flow Fractionation (EAF4) system designed to enhance separation and characterization of biopharmaceutical, environmental and nanomaterials. In an EAF2000 system Electrical and Cross Flow Fields are applied simultaneously enabling separations by particle size and particle charge based on electrophoretic mobility for characterizing complex proteins, antibodies and viruses as well as environmental and charged nanoparticles or polymers. Learn more

Biotech AB presents

The new IDEX QuickStart™ pressure sensor is an in-line, modular, compact sensor that you can easily implement into your fluidic. Easily manage and receive accurate, instantaneous data on system performance. Learn more

Application Note

Automated Extraction of Aflatoxin M1 from Milk

Analytical testing is crucial for maintaining food safety. Food testing labs need reliable automated methods that standardize sample handling and free up skilled staff. Learn more

Upcoming Webcasts

Editors' Series: GC×GC–TOF-MS in Food and Feed Control: Going Beyond Dioxin Measurements

Friday, Oct. 26, at 11am EDT | 8am PDT | 4pm BST | 5pm CEST
Register>>

The CHROMacademy Essential Guide to: N-Glycan Sample Preparation and Analysis Workflows for Screening and Characterization of Biotherapeutics

Improved Protein/Variant Recovery, Selectivity, and Reproducibility with New Monosized WCX Particle Technology

Thursday, Nov. 1, 2018 at 11am EDT | 8am PDT | 3pm GMT | 4pm CET
Register>>

Expanding the Limits of Single-shot Proteomics Using Micro Pillar Array Columns and Data-Independent Acquisition (DIA) Methods

Monday, Nov. 5, 2018 at 9am EST | 2pm GMT | 3pm CET
Register>>

Ease Routine Analysis of Phthalates in Vegetable Oil with Enhanced Sensitivity and Robustness from Single Quadrupole GC-MS Advanced EI source

Tuesday, Dec. 4, 2018 at 11am EST | 8am PST | 4pm GMT | 5pm CET
Register>>

The LCGC Blog: Improve Sensitivity and Reproducibility Using Pulsed Pressure Splitless GC Injection

CASSS' CMC Strategy Forum Japan is 3-4 December 2018 in Tokyo

Py-GC–MS Analysis of Japanese Jõmon Period Lacquerware

Tips, Tricks, and Troubleshooting for Separations of Biomolecules, Part 2: Contemporary Separations of Proteins by Size-Exclusion Chromatography

Safely Delivering the Best Possible Carrier and Detector Gases to Your GC System

Analytical Life Cycle Management– The Coming Revolution

FEATURED PRODUCTS

Analysis of Phospholipids with iHILIC^®-Fusion

Separation & Characterization of Complex Charged Molecules with Electrical Field-Flow Fractionation.

Biotech AB presents

Application Note

Automated Extraction of Aflatoxin M1 from Milk

Upcoming Webcasts

Editors' Series: GC×GC–TOF-MS in Food and Feed Control: Going Beyond Dioxin Measurements

The CHROMacademy Essential Guide to: N-Glycan Sample Preparation and Analysis Workflows for Screening and Characterization of Biotherapeutics

Improved Protein/Variant Recovery, Selectivity, and Reproducibility with New Monosized WCX Particle Technology

Expanding the Limits of Single-shot Proteomics Using Micro Pillar Array Columns and Data-Independent Acquisition (DIA) Methods

Gas Chromatography with Vacuum Ultraviolet Detection for Pharmaceutical Analysis

Enhanced Environmental Monitoring, Part 2: Five High-Throughput Lab Applications of Direct MS

Addressing the Analytical Challenges of Reversed-Phase Characterization of Protein Therapeutics

Your Guide to Water Purification for LC-MS

Enhanced Environmental Monitoring, Part 3: Direct MS for Demanding Air Quality Applications

Ease Routine Analysis of Phthalates in Vegetable Oil with Enhanced Sensitivity and Robustness from Single Quadrupole GC-MS Advanced EI source

ON DEMAND WEBCASTS

Natural Product Purification by Centrifugal Partition Chromatography (CPC)

Challenges in Extracting Perfluorinated Compounds in Drinking and Wastewaters

Challenges and Solutions for Sugar Analysis in Human Food, Animal Feed, and Pet Food

Screen Hundreds of N-Glycans per Day: More Samples – Better Decisions – Faster

Gain Insights into Compliance Trends and Better Prepare for FDA Audits

Laboratory Water Preparation – Optimized

Strategically Selecting the Best Superficially Porous Particle LC Column for Your Method Development

The Multi-Attribute Method (MAM): Advancing Biopharmaceutical Discovery, Development, and Manufacturing

Rapid Low-level Identification and Quantitation of Host Cell Proteins

Multi-class Veterinary Drug Quantitation with a Comprehensive Workflow

A Useful Method Development Strategy for Larger Protein Variant RPLC Separations

Addressing Data Integrity Challenges when Relying on Spreadsheets for Calculating and Documenting Laboratory Results