The LCGC BLOG

Three Peaks Shapes You Really Don't Want to See in Your Gas Chromatogram

Sometimes troubleshooting a separation can rely upon the end user spotting subtle clues within the chromatogram, and at other times the visual signs can be much more obvious. I like to include real world examples in my teaching, as they more effectively portray the appearance of peaks and baselines which are not as they should be. This helps students to fine tune their "trouble radar" and to spot issues as they occur – accelerating the experiential learning that may otherwise take months and years to accumulate. read more

Join CASSS for Analytical Technologies Europe: Symposium on the Practical Applications including CE, LC and MS in the Biopharmaceutical Industry taking place 6-9 March 2018 in Barcelona, Spain. AT Europe provides an active forum for discussion, including roundtable sessions and a panel discussion after each session. Learn more and register now!

Features

GC: The State of the Art

In this extended special feature to celebrate the 30th anniversary edition of LCGC Europe, leading figures from the separation science community explore contemporary trends in separation science and identify possible future developments. We asked key opinion leaders in the field to discuss the current state of the art in gas chromatography instruments. read more

The Revival of SFC in Pharmaceutical Analysis

There has been a great renewal of interest in supercritical fluid chromatography (SFC) as a performing analytical tool for various types of applications recently. SFC is particularly suitable for pharmaceutical analysis, where it is required to have separation methods offering high throughput, elevated efficiency, and, importantly, sensitivity for the determination of drugs in various matrices, such as drug formulation and biological fluids. However, SFC has also been used for other applications, including food analysis, polymer analysis, and environmental analysis, as reported in a recent review. read more