Lead Story

Peak Shapes and Their Measurements: The Need and the Concept Behind Total Peak Shape Analysis

Gaussian peak shapes in chromatography are indicative of a well-behaved system. Such peak shapes are highly desirable from the perspective of column packing technology. Here, we discuss a number of approaches for peak shape measurement that are available in modern chromatography software, along with their advantages and drawbacks. A new "total peak shape analysis" approach is suggested that facilitates detection and quantification of concurrent fronting and tailing in peaks. Several remediation approaches are proposed that can help chromatographers analyze and improve peak shapes. read more

The Safe Hydrogen Gas Solution for GC

The VICI DBS range of FID Gas Stations with sophisticated software control and alarm capability present the GC user with the opportunity to reap all the benefits offered by hydrogen carrier gas, whilst overcoming the safety concerns. These unique instrument combines the reliability of the VICI DBS hydrogen and zero air generators into one compact and convenient FID package. Learn more

Features

Particles, Pressure, and System Contribution: The Holy Trinity of Ultrahigh-Performance Liquid Chromatography

The last decade has witnessed how liquid chromatography columns and instruments changed from long bulky columns with relatively large fully porous particles operated at modest pressures (100–200 bar), to short compact columns with small superficially porous particles operated at ultrahigh pressures (1200–1500 bar). This (r)evolution has resulted in a tremendous increase in achievable separation performance or decrease in analysis time but requires a good knowledge of optimal chromatographic conditions for each separation problem and, concomitant, the right instrument configuration. read more

A New Era for Big Data and Chromatography

We have entered a new stage in the era of accelerations. Moore’s law continues its expansion, increasing exponentially the computer power available. Other accelerations are remarkable, particularly easy access to cloud computing and the expansion and influence of artificial intelligence to practically all sectors of our society. read more

News

Detecting Emerging Pollutants in Leafy and Root Vegetables

Researchers from the University of Seville have developed a method for the determination of pollutants in leafy and root vegetables using ultrasound-assisted extraction (UAE), dispersive solid-phase extraction (d-SPE), and liquid chromatography tandem mass spectrometry (LC–MS/MS). read more