LCGC Blog
The proposed changes to USP Chapter <621> include the allowable adjustment to the eluent composition, further qualification of changes to the stationary phase as well as, critically, some guidance on allowable changes to the gradient profile. What might this mean in practice?
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Features
Tips on how to select a hydrophilic interaction chromatography (HILIC) stationary phase. Read more
Our annual review of new liquid chromatography columns and accessories, introduced at Pittcon and other events. Read more
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News
Researchers from the University of Gothenburg, in Gothenburg, Sweden, have investigated whether plasma amino acid levels differed among children with celiac disease using LC–MS. Read more
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Application Notes
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Presented is a SPE procedure for fentanyl, norfentanyl, and eleven designer compounds. The method accurately seperates fentanyl from any other novel compounds that may be present.
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This technical overview demonstrates the orthogonal separation of a mixture of pesticides using a SFC/UHPLC hybrid system including performance data of both modes.
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FEATURED PRODUCTs
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VICI Precision Sampling Magnum Series syringes specially formed seals permit leak-tight operation to 30 psi. Built-in twist-lock valve and positive rear plunger stop. Up to 500 ml capacity.  / Learn more / |
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The DAWN HELEOS II is the most advanced multi-angle light scattering instrument for characterization of macromolecules and nanoparticles in solution to determine absolute molar mass and size.  / Learn more / |
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PharmaFluidics' game-changing chip-based chromatography column for nano-LC, lets you detect more molecules in tiny, complex biological samples: excellent separation, unprecedented robustness and reproducibility, perfect for lipidomic, metabolomic and peptide profiling.  / Learn more / |
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Silicone impact support mats from Porvair Sciences are designed to protect deep well microplates when they are being centrifuged. Fitting snugly into the skirt of the deep well plates, silicone impact support mats allow plates to be used in a centrifuge without risking plate distortion, cracking or breaking, resulting in well leakage and loss of valuable samples. Impact support mats are now available for Porvair Sciences square deep well plates (2ml, 1ml and 350ul), round well plates (2ml & 1ml) and range of large volume deep well plates.  / Learn more / |
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Postnova Analytics announces the launch of the EAF2000 - an innovative new simultaneous Electrical and Asymmetrical Flow Field Flow Fractionation (EAF4) system designed to enhance separation and characterisation of biopharmaceutical, environmental and nanomaterials. / Learn more / |
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UHPLC and HPLC HILIC columns with three different surface chemistries, iHILIC®-Fusion, iHILIC® Fusion(+), and iHILIC®-Fusion(P), provide customized and complementary selectivity and excellent durability. They are versatile for the LC–MS analysis of polar compounds in "Omics" researches, food and beverage analysis, pharmaceutical discovery, and clinical diagnostics. Email: info@hilicon.com  / Learn more / |
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