The LCGC Blog
If given the need to determine drug A or its metabolite in blood, 99% of the time I would choose to start with liquid chromatography–mass spectrometry (LC–MS).
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We are pleased to announce the introduction of the new 200 ml/min Nitrogen Generator. Using a slim line space saving cabinet it can support 1 to 6 GC's with make-up or carrier gas. The new version is available with the integrated catalyst module to provide the highest purity nitrogen free from hydrocarbons, ideal for all GC applications including ECD.
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Features
This article details the potential of HPLC and MS with regard to revealing methionine oxidation, a chemical modification that may be induced during downstream processing and storage of biopharmaceuticals. Read more
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BioPureSPN™ Graphite SPE utilize an activated charcoal bed to both desalt and remove particles. Try BioPureSPN spin columns today for reproducible, high capacity desalting. Now in 96-Well, hybrid weight formats! Tested and proven by leading proteomic laboratories around the world. The Nest Group, Inc. - "Not Just Columns … Answers!"
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Is that peak "pure"? How do I know if there might be something hiding under there? Read more
A preview of the 32nd International Symposium on Chromatography (ISC 2018), which will be held on 23–27 September 2018 in Cannes-Mandelieu, France. Read more
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News
Researchers from the Université de Pau et des Pays de l'Adour, in France, have developed a large volume injection method using a programmed temperature vaporization (PTV) injector for the simultaneous determination of mercury, tin, and lead at ultra-trace levels in natural waters using GC–ICP-MS. Read more
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Application Notes
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This application note shows the development of an SFC method for the chiral separation of D- and L-amphetamine and the analysis of an authentic whole blood sample.
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This App Note discusses the 6120B Single Quadrupole Walkup system, and its practical use for applications including the analysis of chemical libraries.
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