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LCGC Europe
July 12, 2018
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The LCGC Blog

Optimizing Sensitivity in Splitless Capillary GC with FID Detection

It is often possible to achieve better sensitivity and lower limits of detection and quantitation using standard gas chromatography (GC) equipment—here I'm referring to a standard split/splitless injection port and a Flame Ionization Detector (FID). Paying attention to some of the fundamental variables as well as some of the more esoteric considerations can lead to much improved method performance.
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NEW! Ultra-High Purity Nitrogen Generator

We are pleased to announce the introduction of the new 200 ml/min Nitrogen Generator. Using a slim line space saving cabinet it can support 1 to 6 GC's with make-up or carrier gas. The new version is available with the integrated catalyst module to provide the highest purity nitrogen free from hydrocarbons, ideal for all GC applications including ECD. Learn more


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Features

Frontiers in Ultrafast Chiral Chromatography

This article discusses the advances in ultrafast enantiomeric separations and will conclude with the latest developments in the field that have managed to achieve separations in the sub-second domain. Read more


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Impact Support Mats Protect Microplates During Centrifugation

Silicone impact support mats from Porvair Sciences are designed to protect deep well microplates when they are being centrifuged. Fitting snugly into the skirt of the deep well plates, silicone impact support mats allow plates to be used in a centrifuge without risking plate distortion, cracking or breaking, resulting in well leakage and loss of valuable samples. Impact support mats are now available for Porvair Sciences square deep well plates (2ml, 1ml and 350ul), round well plates (2ml & 1ml) and range of large volume deep well plates. Learn more


Quantifying Aquatic Toxins Using UHPLC–MS/MS

LCGC Europe spoke to Andrew Turner, Principal Chemist in the Food Safety Group at the Centre for Environment, Fisheries, and Aquaculture Science (Cefas) in Weymouth, UK, about developing a simple ultrahigh-pressure liquid chromatography tandem mass spectrometry (UHPLC–MS/MS) method for the quantitation of microcystins and nodularin in various sample matrices. Read more

ISC Event Preview

A preview of the 32nd International Symposium on Chromatography (ISC 2018), which will be held on 23–27 September 2018 in Cannes-Mandelieu, France. Read more


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ACE HILIC Method Development Kits

ACE HILIC Method Development Kits group together the acidic character ACE HILIC-A phase, the basic character ACE HILIC-B phase, and the neutral character ACE HILIC-N phase – each offering alternative selectivity – to provide you with a powerful screening platform for the development of a successful and robust HILIC separation. Available in 1.7, 3, and 5µm and a variety of column dimensions. Advanced Chromatography Technologies Limited, Scotland, UK Learn more

News

Combatting Stink Bug Infestations Using VOC Analysis and GC–MS

Researchers from Lincoln University, Lincoln, New Zealand, have investigated the potential of volatile organic compound (VOC) analysis using gas chromatography–mass spectrometry (GC–MS) to identify the presence of the agricultural and urban pest the brown marmorated stink bug. Read more

Application Notes

Determination of Pesticide Residues in Soil

QuEChERS was successfully used for the extraction and cleanup of 21 pesticides from soil. LC-MS/MS was used for detection and quantitation. / Learn more /

IDP Scroll Pump Evaluation on MS

This application note compares the Agilent IDP-10 Dry Scroll Vacuum Pump and Oil Roughing Pump on the Agilent Intuvo coupled to the 7010B Triple Quad MS. / Learn more /


FEATURED PRODUCTs

DAWN HELEOS II

The DAWN® HELEOS® II is the premier Multi-Angle static Light Scattering (MALS) detector for absolute characterization of the molar mass and size of macromolecules and nanoparticles in solution. / Learn more /

Backpressure regulation up to 300bar

As an extension to the VICI Jour® Back Pressure Regulators the new JR-BPR3 offers an extended application range. Pressures from 90-300bar (1300-4200psi) are easily manual adjustable. The body is made of stainless steel and the inert membran bar enables the usage of any HPLC mobile phase and of supercritical CO2. The JR-BPR3 can also be mounted into any column oven up to 80°C. / Learn more /

µPAC™ - Next-level chromatography

PharmaFluidics' game-changing chip-based chromatography column for nano-LC, lets you detect more molecules in tiny, complex biological samples: excellent separation, unprecedented robustness and reproducibility, perfect for lipidomic, metabolomic and peptide profiling. / Learn more /

Separation & Characterization of Complex Charged Molecules with Electrical Field-Flow Fractionation.

Postnova presents an innovative new simultaneous Electrical and Asymmetrical Flow Field-Flow Fractionation (EAF4) system designed to enhance separation and characterization of biopharmaceutical, environmental and nanomaterials. In an EAF2000 system Electrical and Cross Flow Fields are applied simultaneously enabling separations by particle size and particle charge based on electrophoretic mobility for characterizing complex proteins, antibodies and viruses as well as environmental and charged nanoparticles or polymers. / Learn more /

Immobilised sub-2 Columns

Daicel's META immobilised column screening set is available in sub-2 micron particle size. The CHIRALPAK® IA-U, IB-U, IC-U & IG-U screening set offers: ULTRAFAST SEPARATION, HIGHER RESOLUTION POWER and SOLUTIONS IN SECONDS. Daicel's newest immobilised column CHIRALPAK IH is also available to order in 5- and 3-µm particle size. / Learn more /
Chiral Technologies Europe SAS, Illkirch, France.

Innovative HILIC Columns

UHPLC and HPLC HILIC columns with three different surface chemistries, iHILIC®-Fusion, iHILIC® Fusion(+), and iHILIC®-Fusion(P), provide customized and complementary selectivity and excellent durability. They are versatile for the LC–MS analysis of polar compounds in "Omics" researches, food and beverage analysis, pharmaceutical discovery, and clinical diagnostics. Email: info@hilicon.com / Learn more /


UPCOMING WEBCASTS

Enhanced Simple Sugar Retention and Resolution Using an Innovative and Robust HILIC Phase

Friday, 13 July, 2018 at 11 am EDT | 8 am PDT | 1600 BST | 1700 CEST
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High-Throughput, Automated Volatiles Analysis in Air, Polymers, Water and Soil, Using Direct MS

Europe Broadcast: Wednesday, 18 July, 2018 at 1300 BST | 1400 CEST
US Broadcast: Wednesday, July 18, 2018 at 11 am EDT | 10 am CDT | 8 am PDT
Register>>

Better Characterize Your New Biologics with Robust High-Resolution Charge Heterogeneity Analysis

Europe Broadcast: Thursday, 19 July, 2018 at 1400 BST | 1500 CEST
US Broadcast: Thursday, July 19, 2018 at 11 am EDT | 10 am CDT | 8 am PDT
Asia Pacific Broadcast: Friday, 20 July, 2018 at 1100 CST | 1200 JST | 1300 AEST
Register>>

Enhanced Productivity for VOCs Analysis in Water and Soil by Purge & Trap GC-MS

Wednesday 25 July, 2018 at 11 am EDT | 8 am PDT | 1600 BST | 1700 CEST
Register>>

Eliminating Toxic Contaminants from Cannabis Extracts Using Proven Chromatography Purification Methods

Thursday, July 26, 2018 at 11:30 am EDT | 10:30 am CDT | 8:30 am PDT
Register>>

ON DEMAND WEBCASTS

Overcoming Challenges Associated with Pesticide Residue Analysis in a Complex Cannabis Matrix Using LC-MS/MS


Proven Answers for Protein, Vaccine and Nucleotide Characterization


How to Manage Analytical Methods Across all Stages of their Life Cycle Using One Chromatographic Modeling Tool


Real-Time, High-Sensitivity Food and Flavor Analysis Using Direct MS


Implementing GC-HRAM MS for More Efficient and Effective Routine Pesticide Residues Analysis

 

Editors' Series: Wastewater Analysis as a Tool for Public Health Assessment and Law Enforcement


Determination of Sulfite in Food and Beverages by LC-MS/MS: Method Development, Validation, and Investigation of Problematic Matrices


What Does ISO 17034 Mean for Your Laboratory?


Quantitative Odor Monitoring: Source to Fenceline Analysis Using Direct MS

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