LCGC Blog
Chromatographic methods often require that the analyte response is calibrated (and validated) over a wide concentration range when the analyte concentration in the sample is either unknown or is expected to vary widely. Bioanalysis, environmental, and clinical applications are just a few examples of where this may be the case.
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New EXP UHPLC guard column cartridges are made specifically for Raptor 1.8 µm columns. They provide extreme protection from particulates and matrix contamination, extend the lifetime of already rugged and long-lasting Raptor columns, and are proven to withstand the same UHPLC pressures as their analytical column counterparts. These new guard column cartridges are especially valuable when using dilute-and-shoot or other minimal sample preparation techniques.
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Features
The use of superficially porous particles (SPPs) for modern high performance liquid chromatography (HPLC) is now very common. Initially, SPPs rose as an alternative to sub-2-µm fully porous particles (FPPs). In recent years, many column manufacturers have developed 2-µm and smaller SPP-based products. This article investigates the practical utility of these smaller SPP designs. Read more
The first of three articles looking at the impact of the new USP <1058> on Analytical Instrument Qualification (AIQ) on data integrity in a regulated chromatography laboratory. Read more
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MORE Features
A preview of the 32nd International Symposium on Chromatography (ISC 2018), which will be held on 23–27 September 2018 in Cannes-Mandelieu, France. Read more
News
The Chromatographic Society has announced the "Grass Roots 3" Educational Event is to be held at the Waterhead Hotel, Ambleside, Cumbria, UK, Friday 5–Monday 8 October 2018. Read more
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