September 13, 2018

LCGC Europe Weekly Update
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SEPTEMBER 13, 2018

LCGC Blog

The LCGC Blog: Solve Carryover Problems in Gas Chromatography

Let's first properly define carry-over in the context that I'd like to discuss here. An injection is made and a chromatogram obtained. On injecting a "blank" as the next injection, one or more of the components of the previous injection appear in the "blank" chromatogram.
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Siderophore Biometal HILIC Separations

iHILIC® Fusion column separations assisted identification of 4 new structures for this Siderophore (Biometal) class of high-affinity, iron-chelating compounds which transport iron across cell membranes. Try our iHILIC® Fusion chemistry today for your most demanding HILIC applications. Tested and proven by leading metabolomics laboratories. The Nest Group, Inc. - "Not Just Columns … Answers!" Learn more

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Features

Pressure Tuning: Increasing the Flexibility of Comprehensive Two-Dimensional Gas Chromatography

The role of pressure tuning in extending the scope of comprehensive two-dimensional GC is described. Learn more

Ten Common-Sense Corollaries in Pharmaceutical Analysis by High Performance Liquid Chromatography

This of instalment of “Perspectives in Modern HPLC” describes ten corollaries in high performance liquid chromatography (HPLC) and pharmaceutical analysis that most practitioners are likely aware of but may overlook the rationales behind them. Learn more

ISC Event Preview

A preview of the 32nd International Symposium on Chromatography (ISC 2018), which will be held on 23–27 September 2018 in Cannes-Mandelieu, France. Read more

Genotoxic Impurities | 23-24 October | Hotel Palace Berlin, Berlin

The Genotoxic Impurities conference provides a platform to engage and discuss ideas ranging from experiences of ICH M7 implementation to practical advice from Regulatory Authorities and the latest on novel analytical tools and strategies. Join us in Berlin on the 23-24 October to hear from the brightest industry and regulatory minds as they shine a light on identification and control of Genotoxic Impurities. Learn more

News

Biodiesel-Diesel Blend Analysis Using UFGC

Researchers from the College of the Holy Cross have developed an ultrafast gas chromatography (UFGC) and chemometric method for the analysis of biodiesel blends. Read more

Application Notes

Automated Purification of Compound Libraries

This technical overview demonstrates the automated purification of a compound library in which typical fraction purity and recovery of more than 90% were achieved. / Learn more /

Analysis of Additives in a Polymer

Polymer additives analysis using the Agilent 6120B Single Quadrupole MS and MassWorks accurate mass elemental composition determination software. / Learn more /

FEATURED PRODUCTs

Eclipse DualTec

The Eclipse® DualTec™ system offers both Hollow-Fiber Flow-FFF (HF5) and Asymmetric Flow-FFF (AF4) techniques. Both may be integrated into one instrument and coupled seamlessly to the most advanced light scattering detector for determination of molar mass and nanoparticle size, Wyatt's DAWN® HELEOS® II. / Learn more /

FID Gas Station

This combination VICI DBS hydrogen and zero air generator is available in High and Ultra High Purity for all GC detectors and carrier gases. H2 flow up to 1L/min and 10.5 bar. / Learn more /

µPAC™ - Next-level chromatography

PharmaFluidics' game-changing chip-based chromatography column for nano-LC, lets you detect more molecules in tiny, complex biological samples: excellent separation, unprecedented robustness and reproducibility, perfect for lipidomic, metabolomic and peptide profiling. / Learn more /

Separation & Characterization of Complex Charged Molecules with Electrical Field-Flow Fractionation.

Postnova presents an innovative new simultaneous Electrical and Asymmetrical Flow Field-Flow Fractionation (EAF4) system designed to enhance separation and characterization of biopharmaceutical, environmental and nanomaterials. In an EAF2000 system Electrical and Cross Flow Fields are applied simultaneously enabling separations by particle size and particle charge based on electrophoretic mobility for characterizing complex proteins, antibodies and viruses as well as environmental and charged nanoparticles or polymers. / Learn more /

Immobilised sub-2 Columns

Daicel's META immobilised column screening set is available in sub-2 micron particle size. The CHIRALPAK^® IA-U, IB-U, IC-U & IG-U screening set offers: ULTRAFAST SEPARATION, HIGHER RESOLUTION POWER and SOLUTIONS IN SECONDS. Daicel's newest immobilised column CHIRALPAK IH is also available to order in 5- and 3-µm particle size. / Learn more /
Chiral Technologies Europe SAS, Illkirch, France.

Analysis of Phospholipids with iHILIC®-Fusion

HILICON HILIC columns, iHILIC®-Fusion, iHILIC®-Fusion(+), and iHILIC®-Fusion(P), are versatile for the LC–MS analysis of polar compounds in "Omics" researches, pharmaceutical discovery, and clinical diagnostics. A recent application shows 10 phospholipids (PLs) classes can be well separated by an iHILIC®-Fusion column. The method is applicable for the potential clinical applications. / Learn more /

High Purity Solvents for GC

Find the solvents you need for your GC analysis with our specific product ranges: GC-MS grade, Headspace grade, ATRASOL® for traces analysis in organic compounds and PESTIPUR® grade for pesticides analysis. / Learn more /

UPCOMING WEBCASTS

Addressing Data Integrity Challenges when Relying on Spreadsheets for Calculating and Documenting Laboratory Results

Thursday, 13 September, 2018 at 10 am EDT | 1500 BST | 1600 CEST
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Stable Migration Time in Capillary Electrophoresis SDS (CE-SDS) to Simplify Data Analysis in Chromatography Data Software

Extra Dimensions in 'Foodomics' by GC×GC-TOF MS with Tandem Electron Ionization

Tuesday, 18 September, 2018 at 9 am EDT | 1400 BST | 1500 CEST
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Editors' Series: Controlling Chromatographic Integration to Ensure Data Integrity

Europe: Wednesday, 19 September, 2018 at 1400 BST | 1500 CEST
North America: Wednesday, September 19, 2018 at 2pm EDT | 1pm CDT | 11am PDT
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Sensitive Forensic Screening for Drugs of Abuse in Human Urine Using Single Quadrupole GC-MS and a Simple Solid Phase Extraction

Thursday, 20 September, 2018 at 11 am EDT | 8 am PDT | 1400 BST | 1500 CEST
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Fc Fusion and mAb Glycan Analysis: How does CE compare with HILIC?

5 Ways to Optimize Your CE-SDS Analysis

Advances in Electrolytic Suppression for Ion Chromatography

Simplifying High-Throughput Pharmacokinetic LC-MS Analysis of Monoclonal Antibodies (mAbs)

Strategically Selecting the Best Superficially Porous Particle LC Column for Your Method Development

The Multi-Attribute Method (MAM): Advancing Biopharmaceutical Discovery, Development, and Manufacturing

Wednesday, 3 October, 2018 at 11 am EDT | 8 am PDT | 1600 BST | 1700 CEST
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Challenges and Solutions for Sugar Analysis in Human Food, Animal Feed, and Pet Food

Thursday, 4 October, 2018 at 11 am EDT | 8 am PDT | 1600 BST | 1700 CEST
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Screen Hundreds of N-Glycans per Day: More Samples – Better Decisions – Faster

Gain Insights into Compliance Trends and Better Prepare for FDA Audits

Natural Product Purification by Centrifugal Partition Chromatography (CPC)

Monday, 15 October 2018 at 11 am EDT | 8 am PDT | 1600 BST | 1700 CEST
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The CHROMacademy Essential Guide to: N-Glycan Sample Preparation and Analysis Workflows for Screening and Characterization of Biotherapeutics