November 01, 2018

LCGC Europe Weekly Update
Having trouble viewing this e-mail? CLICK HERE

NOVEMBER 01, 2018

LCGC Blog

The LCGC Blog: Oilfield Wastewater Treatment Is an Opportunity for More Analytical Chemistry

Unconventional oil and gas (UOG) extraction is a multistep process that involves horizontal drilling, hydraulic fracturing, and massive infrastructure to handle fossil fuel resource recovery and associated wastewater generation. Read more

Versatile and Automated Mass Spectrometry-Based Approaches for Monoclonal Analysis

The molecular complexity of monoclonal antibodies (mAbs) makes accurate characterization challenging. This ebook highlights versatile and automated mass spectrometry-based approaches for intact protein analysis, peptide mapping, and glycan analysis that deliver quick and reliable answers. Download the eBook

Subscribers can enjoy each full issue of LCGC in print, or via LCGC apps.

subscription offers

Features

LC–MS Sensitivity: Practical Strategies to Boost Your Signal and Lower Your Noise

Despite its advantages, the complexity of LC–MS systems often leaves analysts struggling to meet method detection limits. In this instalment of "Column Watch", several strategies will be discussed to improve method sensitivity through the reduction of contaminants, the careful selection of LC method conditions, and the optimization of MS interface settings. Learn more

Silicon Wafer Technology Makes LC Analysis for Proteomics More Powerful and Effective: A User's Experience

As the field of proteomics grows more complex, traditional separation techniques like nano-liquid chromatography (LC) have a harder time extracting critical information efficiently. PharmaFluidics' μPAC™, a breakthrough in column design, helps bring LC analysis up to speed. LCGC recently sat down with Geert Van Raemdonck, global field support expert at PharmaFluidics, to discuss this topic. Access the Podcast and Q&A Learn More

IVT's 6th Annual Laboratory Week

IVT's 6th Lab Week conference series draws over 100 laboratory professionals and provides the value of three conferences in one, giving your team the ability to select sessions that best meet your business objectives. Hear from FDA and choose from over 25 workshops, think tanks, interactive presentations, case studies and educational courses surrounding analytical procedures and methods validation, stability testing and lab data integrity. Learn More

Analyzing Phosphorylated N-glycans with Full Recovery on a Bio-Inert LC System and PEEK-Lined HILIC Column

HILIC combined with FLD or MS and 2-AB labeling is nowadays the golden standard for the analysis of N-glycans enzymatically liberated from biopharmaceuticals. However, for phosphorylated N-glycans irreproducible data are obtained on conventional LC instrumentation and columns. For full recovery of phosphorylated species the use of bio-inert LC systems and PEEK-lined HILIC columns is required. Learn more

News

Generic GC–FID for Volatile Amine Quantitation in Pharma

Researchers from Merck and Agilent Technologies have developed a simple and fast generic gas chromatography–flame ionization detection (GC–FID) method for the quantitation of volatile amines in pharmaceutical drugs and synthetic intermediates. Read more

Application Note

LipiFiltr® Cleanup for High-Lipid Food Samples

The application shows the benefits of using the LipiFiltr® cartridge in multi-class, multi-residue analysis for a wide range of pesticides in complex, high fat samples. / Learn more /

Monitoring of Mammalian Cell Culture Media

This application note describes the monitoring of nutrient uptake and excreted waste products in mammalian cell culture media with HILIC LC–MS. / Learn more /

FEATURED PRODUCTs

Sciencix HPLC Check Valve Cartridges

Reduce your product repair expenses by 30% by using our high quality check valve cartridges. Our check valve cartridges are equivalent to the corresponding OEM part. / Learn more /

Upasil® - bulk silica

State-of-the art silicas for your process liquid chromatography. As privately held company we are committed to process our chromatography grade silicas in Europe. / Get in touch! /

NEW SEC Column for Antibodies

The new YMC-SEC MAB is designed for analysing antibodies, fragments or aggregates. It is the ideal choice for high resolution of high and low molecular weight species with excellent reproducibility. / Learn more /

Eclipse DualTec

The Eclipse® DualTec™ system offers both Hollow-Fiber Flow-FFF (HF5) andAsymmetric Flow-FFF (AF4) techniques. Both may be integrated into one instrument and coupled seamlessly to the most advanced light scattering detector for determination of molar mass and nanoparticle size, Wyatt's DAWN® HELEOS® II./ Learn More /