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In our June issue:
COLUMNS:
LC TROUBLESHOOTING
Mixing and Mixers in LC
Adding an inline mixer between the sample injector and column in a liquid chromatography (LC) system can be an effective way to resolve problems with peak shape caused by the sample diluent. This instalment of "LC Troubleshooting" explains more. Read more >>
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BIOPHARMACEUTICAL PERSPECTIVES
Characterizing mAbs and ADCs Using SEC
How size-exclusion chromatography (SEC) in combination with high-resolution mass spectrometry (MS) can be applied to the detailed characterization of monoclonal antibodies (mAbs) and antibody–drug conjugates (ADCs). Read more >>
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Exclusive Videos: Novel Applications for CESI–MS Analysis
At the most recent Global CESI-MS Symposium, researchers explored the use of CESI–MS analysis to characterize monoclonal antibodies, to quantify highly polar pesticides, to identify post-translational protein modifications, to detect pesticide metabolites, and much more.
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THE ESSENTIALS
Solving Recovery Problems in SPE
In this excerpt from LCGC Europe's e-learning platform, CHROMacademy.com, recovery problems in solid-phase extraction (SPE) are discussed.
Read more >>
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FEATURE:
HPLC 2019: Hot Topics
A selection of keynote speakers from HPLC 2019 highlight the latest developments in their areas of expertise. Read more >>
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PEER-REVIEWED ARTICLE:
Transferring Gradient LC Methods
The effect of dwell volume on chromatographic selectivity can be successfully modelled using retention prediction software. Hence, the robustness of reversed-phase liquid chromatography (LC) gradient methodologies, with respect to dwell volume, can be conveniently assessed. Read more >>
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The HPLC 2019 Show Guide Supplement is also featured alongside LCGC Europe's June issue.
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