LCGC Blog
As I receive reports from clients in Europe and the United States that helium prices are once again increasing, and warnings are being given regarding yet another laboratory-grade helium shortage, my thoughts turn once again to the use of hydrogen as an alternative carrier-gas for gas chromatography. Read more
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Sample preparation has several important purposes such as removing interferences, adjusting samples that are too dilute or dirty, and increasing column lifetime and instrument uptime. This ebook offers several tips and tricks for making sample preparation better and more efficient.
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FEATURES
The effect of dwell volume on chromatographic selectivity can be successfully modelled using retention prediction software. Hence, the robustness of reversed-phase liquid chromatography (LC) gradient methodologies, with respect to dwell volume, can be conveniently assessed. Read more
How size-exclusion chromatography (SEC) in combination with high-resolution mass spectrometry (MS) can be applied to the detailed characterization of monoclonal antibodies (mAbs) and antibody–drug conjugates (ADCs). Read more
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The Column spoke to Robert Shaw, Steph Turnbull, and Sophie Bailes from AstraZeneca about their work in quality by design (QbD) in the pharmaceutical industry. Read more
NEWS
A group of researchers has investigated the impact of combined sewer overflow (CSO) on pharmaceutical and illicit drug use in central London using liquid chromatography–high-resolution mass spectrometry (LC–HRMS). Read more
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FEATURED PRODUCT
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The NM Plus 1350 uses the same space saving cabinet as the existing NM range, but now with a higher flow rate of 1350 ml/min.  / Learn more / |
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