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The analysis of biopharmaceutical compounds is complicated for numerous reasons. This ebook explores how analysts can address some common issues related to the analysis of biomacromolecules like monoclonal antibodies and antibody–drug conjugates.
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Features
Is gas chromatography (GC) a mature technology? LCGC Europe spoke to Ronda Gras about a range of GC projects she has been working on to extend the scope of the technique, including a multi-hyphenated approach combining three modes of detection, a miniaturized micromachined GC system, and a novel in situ method to detect carbon dioxide in various matrices by incorporating 3D-printing technology in a flame ionization detector (FID).
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Is a mixer needed between the injector and column in high performance liquid chromatography (HPLC)?
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News
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The analysis of skeletal remains using gas chromatography–mass spectrometry (GC–MS) from Gaul settlement excavations in Southern France has confirmed the ritualistic practice of head embalming in ancient Gaul culture.
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Application Note
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This application shows chiral method development for both SFC and UHPLC using the Agilent 1260 Infinity II SFC/UHPLC Hybrid System with software aided method scouting.  / Download Application Note / |
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FEATURED PRODUCTs
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PharmaFluidics' game-changing chip-based chromatography column for nano-LC, lets you detect more molecules in tiny, complex biological samples: excellent separation, unprecedented robustness and reproducibility, perfect for lipidomic, metabolomic and peptide profiling.
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The new YMC-SEC MAB is designed for analysing antibodies, fragments or aggregates. It is the ideal choice for high resolution of high and low molecular weight species with excellent reproducibility.  / Learn more / |
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Postnova introduces the powerful Triple Detection for Thermal Field-Flow Fractionation (FFF) and GPC/SEC. Triple Detection is the combination of Multi-Angle Light Scattering (MALS), Viscosity Detection, Refractive Index Detection and UV Detection. In a single separation experiment Triple Detection provides molar mass distribution, molecular size distribution and molecular structure (branching, composition) of polymers, biopolymers, polysaccharides, proteins and antibodies.
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