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LCGC Europe
FEBRUARY 07, 2019
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LCGC Blog

Would Your Process Benefit from Multivariate Optimization?

If you have a method or process that involves a number of different variables, multivariate optimization approaches can provide a faster route to optimum conditions and can lead to a more reliable outcome than using a one-factor-at-a-time approach. With a little study and practice, students and researchers can apply these optimization techniques, even if a complete understanding of the underlying statistical treatments is not immediately apparent.
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Boron Nitride Nanotubes

Boron Nitride Nanotube is a next-generation nano-material which will lead the 4th industrial revolution. The key features that represent BNNTs are light weight, mechanical strength and stability like Carbon Nanotubes. BNNTs thermal oxidation resistance is stable up to 800°C in air and it is considered to be one of the most suitable materials for the containers of radioactive waste, space /artificial satellites and biomedical applications. / Learn more /


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Features

Drawing a Better Map: Recent Advances in Protein Digestion and Peptide Mapping

With the increased interest in biotherapeutics, there has been a concomitant increase in new analytical methods for characterizing these large, complex molecules. This instalment of "Column Watch" discusses advances in "bottom-up" analysis of monoclonal antibodies, while highlighting the role and importance column chemistry still plays in developing highly selective HPLC methods for peptides. Read more


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Keep Your LC Flowing

Restek has expanded its line of LC accessories to bring you even more of what you need to keep your LC flowing. Browse top-quality couplers, fittings, unions, tees, and crosses; PEEK and stainless steel tubing; mobile phase maintenance and safety products including bottle tops, valves, filters, and spargers—and that's on top of our already wide selection of instrument replacement parts and supplies. Don't stop at the column; outfit your entire LC system with Restek LC products. / Learn more /

 

Letting the Chromatograph Talk, Part 1–Looking for Troubleshooting Clues in Unexpected Places

Is an ultraviolet (UV) detector signal good for anything if the analyst is using a mass spectrometer? In this month's instalment of "LC Troubleshooting", Dwight R. Stoll discusses two places to find clues that are easily overlooked – the pressure trace recorded by the LC pump, and UV detector signals at low wavelengths. Learn more


News

Novel Flow-Confinement Concept for LC×LC

A novel flow-confinement concept designed to remove the performance sacrifice associated with current comprehensive two-dimensional liquid chromatography techniques has been tested by researchers. Read more

FEATURED PRODUCT

Backpressure regulation up to 300 bar

JR-BPR3 VICI Jour® Back Pressure Regulator. Manually adjust pressure from 90-300bar (1300-4200psi). Stainless steel casing and an inert membrane bar. Mountable into any column oven up to 80°C. / Learn more /

Application Note

Chiral SFC Method Development for Non-Chromatographers

An easy-access method development system for chiral SFC is shown that empowers non-chromatographers to meet the majority of their development needs without expert help. / Learn more /

UPCOMING WEBCASTS

Expanded Mycotoxin LC-MS/MS Analysis in Cannabis Matrices

Thursday, February 7, 2019 at 11am EST | 8am PST | 4pm GMT | 5pm CET
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Extraction of Pesticides from Difficult Food Matrices

Thursday, Feb. 21, 2019 at 11am EST | 8am PST | 4pm GMT | 5pm CET
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The Importance of Computer System Validation for Regulated Systems

Tuesday, Feb. 26, 2019 at 2pm GMT | 3pm CET | 2pm EST | 1pm CST | 11am PST
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Native Mode Mass Spectrometry Analysis

Wednesday, Feb. 27, 2019 at 11am EST | 8am PST | 4pm GMT | 5pm CET
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Achieving PEEK-like Performance on Stainless Steel HPLC Components with Bio-Inert CVD Coatings

Thursday, Feb. 28, 2019 at 11am EST | 8am PST | 4pm GMT | 5pm CET
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ON DEMAND WEBCASTS

Syringe Filters: Take the Guesswork Out of Selection


A Streamlined Approach for Reversed-Phase Method Development Using a Combined Column Screening and Software Modeling Approach


PFAS in Water Treatment Plants: Analysis, Sources, Fate, and Environmental Impact


Latest SEC Methods of Analysis for Biocompatible Polymers Used in Medical Products


Fast and Accurate Sugar, Acid, and Sulfite Analysis Using Automated Discrete Analysis


Moving to the Cloud: Key Considerations


Screen Hundreds of N-Glycans per Day: More Samples – Better Decisions – Faster


Probing Submicron Protein Aggregation Using Asymmetrical Flow Field-Flow Fractionation (AF4) and Light Scattering


 

Moving to the Cloud: Key Considerations


Leveraging Exception Reporting to Optimize Chromatography Data Review


Ease Routine Analysis of Phthalates in Vegetable Oil with Enhanced Sensitivity and Robustness from Single Quadrupole GC-MS Advanced EI source


A Multi-mode LC Approach to Biosimilar Characterization


A Rapid, Simple, and Efficient Extraction Method for Additives in Plastics


Addressing the Analytical Challenges of Reversed-Phase Characterization of Protein Therapeutics


Your Guide to Water Purification for LC-MS


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