LCGC Europe Weekly Update
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LCGC Europe
MARCH 07, 2019
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LCGC Blog

The LCGC Blog: You Can Perform Multiple Reaction Monitoring for an Intact Antibody on a Triple Quadrupole Mass Spectrometer

Virtually exclusively, liquid chromatography–mass spectrometry (LC–MS)-based assays for protein quantitation rely on bottom-up strategies, where the protein is initially digested into constituent peptides during sample preparation. Top-down intact protein quantitation, especially using affordable, low resolution triple quadrupole (QQQ) mass spectrometers, has been largely unexplored.
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EuroLab and CrimeLab at the Palace of Culture and Science
21st International Trade Fair of Analytics and Measurement Technology EuroLab and 8th Criminological Technology Fair CrimeLab will be held from 13 to 15 March 2019 at the Palace of Culture and Science in Warsaw. As usual, the fairs will be accompanied by numerous seminars, lectures, conferences, workshops and business meetings. Learn more.


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Features

GCxGC: From Research to Routine

This instalment of "GC Connections" begins with a brief introduction to GC×GC, follows with examples of how GC×GC opens additional avenues of analysis, and it concludes with information about how to learn more. Read more


What's Trending in LC Troubleshooting?

The challenges we face in troubleshooting problems with liquid chromatography (LC) separations are highly diverse. This month we take a closer look at topics that have garnered more attention recently. Read more

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University students and staff get 5 years of FREE access to CHROMacademy made possible by Agilent Technologies–the world's premiere measurement company. Learn more.


News

Novel Flow-Confinement Concept for LC×LC

A novel flow-confinement concept designed to remove the performance sacrifice associated with current comprehensive two-dimensional liquid chromatography techniques has been tested by researchers. Read more


FEATURED PRODUCTS

Dextran ReadyCal Kit

New in the PSS ReadyCal family for fast calibration of aqueous GPC/SEC systems are the Dextrans:
  • 9 different standards, Mp 180 – 298 000 Da
  • 3x5 1.5ml Vials (5 calibrations)
/ Learn more /

New HPLC Column for quick Evaluation of ADCC Activity

TSKgel FCR-IIIA-NPR, a new HPLC column based on recombinant FcγIIIa receptor - a key player in antibody-dependent cell-mediated cytotoxicity (ADCC) - allows fast evaluation of biologic activity and glycoform pattern of antibodies.
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Bullet-Proof Mapping/Validation Studies

Learn five simple rules to make mapping studies unassailable. The rules ensure that you can effectively determine/document conditions in environments
Webinar: Mapping Made Easy
Date: March 20, 2019
/ Learn more /

NEW NM 1350 Plus Hydrogen Generator

The newest hydrogen generator from VICI DBS, the NM Plus 1350 uses the same space saving cabinet as the existing NM range, but now with a higher flow rate of 1350 ml/min.
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BIOTECH DEGASi® PREP+ Degasser

•  An in-line, membrane degasser
•  Suitable for aggressive media and organic solvents
•  Flow-rates up to 75-100 ml/min per channel
•  Delivered as Standalone or OEM open frame
•  Available with 1-4 channels
/ Learn more /


UPCOMING WEBCASTS

A Confident Approach to Ensure Data Integrity: Leveraging Experts to Assess the Data Lifecycle in Your Laboratory

Thursday, Mar. 28, 2019 at 10am EDT | 2pm GMT | 3pm CET
Register>>

Emerging Water Quality Issues: Are You Ready to Monitor PFAS in your Water?

Live Tuesday, Apr. 9, 2019 at 1pm BST | 2pm CEST | 5:30pm IST | 2pm EDT | 1pm CDT | 11am PDT
Register>>

Native Mode Analysis of mAbs and ADCs- Intact Workflow Solutions for Characterizing Biomolecules by HIC and SEC Chromatography Techniques

North America: Tuesday, Apr. 30, 2019 at 11am EDT | 8am PDT | 4pm BST | 5pm CEST
Europe: Wednesday, May 1, 2019 at 9am BST | 10am CEST
Asia Pacific: Thursday, May 2, 2019 at 8:30am IST | 11am CST | 12pm JST
Register>>


ON DEMAND WEBCASTS

Extraction of Pesticides from Difficult Food Matrices


The Importance of Computer System Validation for Regulated Systems


Native Mode Mass Spectrometry Analysis


Achieving PEEK-like Performance on Stainless Steel HPLC Components with Bio-Inert CVD Coatings


Editors' Series: Addressing Data Integrity Gaps: Does Your Lab Have a Strategy?


Syringe Filters: Take the Guesswork Out of Selection


Expanded Mycotoxin LC–MS/MS Analysis in Cannabis Matrices

 

A Streamlined Approach for Reversed-Phase Method Development Using a Combined Column Screening and Software Modeling Approach


PFAS in Water Treatment Plants: Analysis, Sources, Fate, and Environmental Impact


Latest SEC Methods of Analysis for Biocompatible Polymers Used in Medical Products


Fast and Accurate Sugar, Acid, and Sulfite Analysis Using Automated Discrete Analysis


Moving to the Cloud: Key Considerations


Screen Hundreds of N-Glycans per Day: More Samples – Better Decisions – Faster


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