LCGC Blog
We have been working to develop the use of liquid chromatography–triple quadrupole–mass spectrometry (LC–MS/MS) for quantification of intact proteins from biological fluids.
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Protein-Ligand Library Screening
Shorten the timeline between target and hit identification. A proven LC-MS coupled column automated binding assay allowing ~12K compound/week low hit rate library screening. Try this solution-based affinity selection, SEC-RPC coupled column assay today!
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Features
Isabelle Kohler from Leiden University, in Leiden, The Netherlands, spoke to LCGC Europe about the latest trends in clinical metabolomics using chromatography and how the field is likely to evolve in the future. Read more
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Eliminate the Impact of PFAS Contamination in Your LC
PFAS contamination from HPLC components can prevent accurate measurement of PFAS in samples. To eliminate this issue, Restek's new PFAS delay column traps and "delays" system-related PFAS, preventing them from interfering with sample analysis. This delay column is a universal solution that can be used with any type of HPLC or UHPLC system up to 15,000 psi (1034 bar) and with any analytical column (fully porous or superficially porous).
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"GC Connections" presents the column's annual review of new developments in the field of gas chromatography seen at Pittcon and other venues in the past 12 months.
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Euroanalysis 2019
On behalf of the Turkish Chemical Society, we cordially invite you to join us for the Euroanalysis XX Conference to be held from September 1st to 5th, 2019 in our beautiful city of Istanbul, Turkey. The meeting will be hosted by the Analytical Chemistry Division of the Turkish Chemical Society and the local organizers Ankara University and Istanbul University in collaboration with Division of Analytical Chemistry of Euroapean Association for Chemical and Molecular Sciences (DAC-EuChemS).
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This is the fifth in a series of articles exploring current topics in separation science that will be addressed at the HPLC 2019 conference in Milan, Italy, from 16–20 June.
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Micro Pillar Array Column Technology Resource Center
An online resource with useful tools and practical information for separation scientists who want to find out more about how micro-pillar array columns can benefit the laboratory scientist in practice. The site provides useful technical notes, video interviews, and executive summaries of cutting-edge applications from leading practitioners in the field of proteomics and biopharmaceutical applications.
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When analytical chemists apply green chemistry approaches, which seek to minimize negative environmental effects, an important area of focus is reducing the consumption of toxic solvents, such as those used in extraction steps in sample preparation. Developing and testing greener extraction processes for food analysis is a major focus of Elena Ibáñez, a research professor at CIAL-CSIC in Madrid, Spain.
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News
Researchers have analyzed sediment core from a lake located in the northern foothills of Alaska's Brooks Range to investigate the Beringian standstill hypothesis (BSH) of human migration into the Americas.
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John R. Yates III, a professor in the Department of Molecular Medicine at The Scripps Research Institute, will receive the John B. Fenn Award for a Distinguished Contribution in Mass Spectrometry at the American Society for Mass Spectrometry (ASMS) conference on Monday, June 3, at the Georgia World Congress Center in Atlanta, Georgia.
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FEATURED PRODUCTS
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Antec's ROXY EC System allows for rapid generation of drug metabolites (mimicking metabolism) without biological interactions, unlike in-vivo or in-vitro studies, and easier prediction of the metabolic pathway using EC-MS / Learn more / |
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DAICEL now offers a full set of sub-2 micron columns: CHIRALPAK IA, IB, IC, ID, IG, and IH. This full set offers ultrafast separations, higher resolution power, and results in seconds.
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Centri® – a multi-technique sample automation, pre-concentration and injection platform for GC that delivers enhanced analytical sensitivity and higher throughput for VOC and SVOC analysis in liquid, solid and gas samples. / Learn more / |
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COSMOSIL SFC columns have been developed to enhance SFC separations, with 6 stationary phases for high- and low-polarity compounds and unique separations using secondary interactions. /Learn more/ |
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TSKgel FCR-IIIA-NPR, a new HPLC column based on recombinant FcγIIIa receptor - a key player in antibody-dependent cell-mediated cytotoxicity (ADCC) - allows fast evaluation of biologic activity and glycoform pattern of antibodies. /Learn more/ |
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Our new fitting connects a 360 μm FS tube directly into a 1/16" fitting detail, with the bore of the FS tube precisely aligning with the bore of the valve. /Learn more/ |
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Application Note
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This study outlines the analysis of pharmaceuticals and personal care products (PPCPs) in environmental and drinking water using direct injection LC–MS and online SPE.
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UPCOMING WEBCASTS
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