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Columns
SAMPLE PREP PERSPECTIVES
The Use of Hollow Fibers in Liquid-Phase Microextraction
Limian Zhao, Hian Kee Lee, and Ronald E. Majors
In this installment, the subject of LPME is reviewed, with emphasis on the use of hollow fibers.
LC TROUBLESHOOTING
System Contamination
John W. Dolan
Deterioration of a separation can result from many causes. This month’s column looks at some techniques to isolate the problem source.
BIOTECHNOLOGY TODAY
Biosimilars: Introduction, Concerns, and Opportunities
Anurag S. Rathore and Ira S. Krull
The authors provide an introduction to the topic of biosimilars, review the available regulatory guidance, and discuss the various scientific challenges that are present.
HISTORY OF CHROMATOGRAPHY
Early Adventures in Chromatography: The Story of a “Recovering” Electrochemist
Peter W. Carr
Well-known industry veteran and LCGC EAB member Peter Carr looks back at the early days of the chromatography field and reflects on his own experiences.
ARTICLES
Why Does It Take So Long To Validate a Chromatography Data System?
Robert D. McDowall
The author examines the process of validating a CDS and describes the trials along the way such as speed of validation, risk management, and so forth.
WEBCASTS
The CHROMacademy Essential Guide to Column Selection for Capillary GC
LIVE WEBCAST: Tuesday, July 13, 2010 at 8:00 AM PT; 11:00 AM ET; 5:00 PM GMT
Recent Advances in UHPLC Column Technologies
LIVE WEBCAST: Wednesday, July 14, 2010 at 8:00 AM PT; 11:00 AM ET; 4:00 PM GMT
New Analytical Methods to Address Expected Food Safety Challenges in the Gulf of Mexico
LIVE WEBCAST: Tuesday, July 27, 2010 at 11:00 AM ET
Molecular Imaging for Localization and Distribution of Proteins, Peptides, Drugs and Metabolites by Mass Spectrometry
LIVE WEBCAST: Thursday, August 12, 2010 at 1:00 PM ET
Investigating the Complementary Nature of Accurate Mass and Nominal Mass MS Technologies for Rapid Structural Identification and Complete Characterization of Major and Low-Level Metabolites
LIVE WEBCAST: Thursday, August 26, 2010 at 11:00 AM EST
The CHROMacademy Essential Guide to Understanding the Mechanisms of Solid Phase Extraction
LIVE WEBCAST: Tuesday, August 17, 2010 at 8:00 AM PT; 11:00 AM ET; 4:00 PM GMT
Method Development in Packed Column Supercritical Fluid Chromatography
LIVE WEBCAST: Wednesday, September 1, 2010 at 11:00 AM -12:00 PM ET
Integrated Solutions to Rapid, QbD-Compliant Method Development
LIVE WEBCAST: Thursday, September 16, 2010 at 11:00 AM EST
Pacesetter
Shimadzu has introduced a new GCMS system offering the highest performance in its class. The GCMS-QP2010 Ultra is capable of twice the data acquisition speed of previous models. This makes it ideally suited for Comprehensive 2D GCMS. In addition, it is also the first GCMS system to feature an ECO mode reducing power consumption by 37 % in the standby mode. More details at
 www.shimadzu.eu
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