Application Note Alert
September 2011 Subscribe
Links to technical insights from sponsored Featured Application Notes on Chromatography Online.
Contact Editor
- Janet Kelsey
Food Safety
Simultaneous Analysis of Water-Soluble Vitamins in Beverages by UHPLC-MS-MS
J. Wang, X. Liu, W.C. Schnute, Thermo Fisher Scientific
A high throughput method for simultaneous determination of 10 WSVs in vitamin-enriched beverages by UHPLC-MS-MS
 
Analysis of (Fluoro) quinolones in Honey with Online Sample Extraction and LC–MS-MS
Y. Hammel, Nestle Research Center; F. Schoutsen and C.P.B. Martins, Thermo Fisher Scientific
A sensitive and reproducible triple quadrupole mass spectrometer method for the quantitation of 12 fluoroquinolones and 4 quinolones in honey using automated extraction is developed.
 
Streamlined Analysis of 400+ Pesticides in a Single Run Using the TSQ Quantum Access MAX Mass Spectrometer and TraceFinder Software
J. Wang, C.T. Yang, J.R. Beck, and D. Ghosh, Thermo Fisher Scientific
More than 400 pesticides are analyzed by triple quadrupole mass spectrometer in a single run using software with built-in workflows for streamlining method development and analysis.
Environmental Testing
Analysis of Triazine Herbicides in Drinking Water Using LC-MS-MS and TraceFinder Software
J.R. Beck, J.K. Humphries, L. Maljers, K. Akervik, C. Yang, D. Ghosh, Thermo Fisher Scientific
Learn about a new method to quantitate triazines at the sub-ppt level using new TraceFinder software coupled with LC-MS-MS.
Quantification of EPA 1694 Pharmaceuticals and Personal Care Products in Water at the ng/L Level Utilizing Online Sample Preparation with LC–MS-MS
K. McHale and M. Sanders, Thermo Fisher Scientific
This application note demonstrates a progressive approach to analyzing PPCPs in environmental sources of water at the ng/L level with online sample preparation using small volumes of water, thus saving time and reducing the cost of analysis.
Sensitive and Accurate Quantitation of Perfluorinated Compounds in Human Breast Milk Using Selected Reaction Monitoring Assays by LC–MS-MS
C. Gu, G. Jiang, R. Szilasie, S. Hassan, A. Zhang, and M. Sanders, Thermo Fisher Scientific
A highly sensitive, accurate, and reproducible analysis and quantitation of six PFCs in neat solution and in human breast milk using selected reaction monitoring (SRM) and H-SRM on a triple quadrupole mass spectrometer.
Clinical Research and Bioanalysis
Quantitative Determination of Testosterone in Plasma Using Unique Automated Online Sample Preparation and LC–MS-MS
M. Kozak, Thermo Fisher Scientific
An automated, interference-free method is used to quantitate testosterone with a low limit of quantitation (LOQ) in plasma. This fast method utilizes automated, online sample preparation technology, coupled with a triple quadrupole mass spectrometer.
 
Quantitative Analysis of 1,25-dihydroxyvitamin D2 and D3 Using Immunoaffinity Extraction with APCI-LC–MS-MS
X. He, G. Damkroeger, and M. Kozak, Thermo Fisher Scientific
A very sensitive method to quantify 1,25-dihydroxyvitamin D by combining immunoaffinity extraction and highly selective APCI with a triple quadrupole mass spectrometer is validated.
 
Screening and Quantification of Multiple Drugs in Urine Using Automated Online Sample Preparation and Tandem Mass Spectrometry
B. Brazdova and M. Kozak, Thermo Fisher Scientific
Learn about a 9-min, sensitive (LOQ 1-50 ng/mL) method to quantitate 30 immunosuppressant drugs using Thermo Scientific TurboFlow technology and a triple quadrupole mass spectrometer.
Proteomics
On-the-Fly Retention Time Shift Correction for Multiple Targeted Peptide Quantification by LC–MS-MS
R. Kiyonami, A. Schoen, V. Zabrouskov, and H. Nguyen, Thermo Fisher Scientific
To demonstrate that on-the-fly retention time shift correction enables use of the same iSRM method on a triple quadrupole mass spectrometer while switching columns or flow rates without missing targeted compounds due to retention time shifts.
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