Application Note Alert
September 2009 Subscribe
Links to technical insights from sponsored Featured Application Notes on Chromatography Online.
Contact Editor
- Janet Kelsey
Featured Application Note:
Globular Proteins and the Calibration of ProSEC 300S Columns
By Greg Saunders; Varian, Inc.
LC/HPLC
Highly reproducible GPC analysis of polypeptides
By Howard Barth, Consultant Tosoh Bioscience LLC, Dr. Li Jia, University of Akron; Tosoh Bioscience

Tosoh Bioscience is an acknowledged global leader in the field of liquid chromatography with a focus on bioseparations. Tosoh’s portfolio encompasses GPC instruments (EcoSEC) and a comprehensive line of media and HPLC columns for all common modes of liquid chromatography.
 

ACN-free HPLC Analysis and Prep Purification of ACP Fragment
By S Ball, K Mapp & Linda L Lloyd; Varian, Inc.

Varian offers robust instrumentation, application-based consumables, and customer-focused services to help solve your analytical challenges. Whether you’re monitoring impurities in water, designing new therapeutic drugs, or developing cleaner fuels, our solutions deliver the sensitivity, flexibility and productivity your laboratory requires.

 

MALS for Proteins
By Mark Tardie and George Karam, Wyatt Technology Corporation

Quality and consistency in reagents is critical to successful drug discovery and development.

 

Eluent Optimization for Small Column Volumes
By Holger Franz, Dionex Corporation

This TN addresses the fluidic optimization of the most common UltiMate 3000 system configuration, namely the Quaternary Standard Analytical System. Its fluidic design is optimized for 3–4 mm bore columns with 10–25 cm lengths. The easiest way to optimize these fluidics for small column volumes that provide significant solvent saving potential is to install the “Viper Capillary Kit, RS system”. Further optimization possibilities with respect to sample loop, eluent pre-heater and detector flow cell are also described.
Miscellaneous
Trace-Level Aliphatic Amines in Cationic Drugs
By N. Harihara Subramanian, P.Manigandan, R. Ganeshjeevan, Ganga Radhakrishnan, A. Wille, A Steinbach; Metrohm

Monitoring levels of low-molecular-weight amines in the presence of strongly retained cationic drugs is a challenging task. In this application note Metrohm offers a solution to this problem by using coupled-column matrix elimination (CCME) to shorten analysis times, protect the column and improve selectivity and sensitivity.
 

Rapid sizing of nanoparticles
By Dr Mebs Surve; Paraytec Ltd.

Paraytec is a dynamic scientific instrument company designing, developing and manufacturing the multi award winning ActiPix range of UV area imaging detectors.  ActiPix is opening up a variety of exciting new life science application areas including proteomics, molecular sizing, biopharmaceutical analysis and microfluidics detection.

 
To advertise or have an application note inserted, contact:

Lee Noyes
+44 1244393111 | Email

Caroline Plant
+44 1244393110 | Email


You are subscribed to %%list.name%% as %%emailaddr%%. To unsubscribe from this list click here.

To ensure delivery to your Inbox, please add %%email.list%% to your address book. If you need help doing this, click here.

Advanstar Communications provides certain customer contact data (such as customers' names, addresses, phone numbers and e-mail addresses) to third parties who wish to promote relevant products, services and other opportunities which may be of interest to you. If you do not want Advanstar Communications to make your contact information available to third parties for marketing purposes, simply call (toll free) 1-866-529-2922 at any time, or fax us at 1-218-740-6417. Outside the U.S., please phone 1-218-740-6395. Contact us by mail at Advanstar Communications Inc., 131 West First St., Duluth, MN 55802-2065, USA.