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30 July 2010
How to improve signal-to-noise
The signal-to-noise (S/N) ratio is of most concern when it makes a significant contribution to the error of the chromatographic measurements. Improving S/N will be beneficial by either increasing the signal, decreasing the noise or both. This week's tip offers advice on how to achieve this with some practical examples. More...
Agricultural centre selects Thermo technology
Thermo Fisher Scientific has announced it will be outfitting a new research centre in Victoria, Australia. More...
Australian company wins technology innovation award
SGE Analytical Science has received a 2010 R&D100 Award for its automated analytical syringe, eVol. More...
Product Profiles
The Column
NEW global launch
The new global edition of The Column is delivered twice monthly with a screen-optimized format designed to improve readability. Covering topical issues, application-based articles, market reports, tips and tricks, opinion pieces and interviews, The Column is a great information resource helping readers achieve better day-to-day working practices.

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Application Notes
AB SCIEX
Identifying Unexpected Environmental Contaminants
This application note describes the use of the AB SCIEX TripleTOF™ 5600 LC/MS/MS System for the screening and identification of unexpected contaminants in lake water, demonstrating the of value of high resolution, accurate mass data and retrospective data processing for the identification of non-targeted compounds.

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Antec
Fast Mimicking of Drug/Xenobiotic Metabolism
With the introduction of the ROXY™ EC system by Antec, mimicking of phase I and II drug/xenobiotic metabolism has become possible within a few minutes, resulting in substantial time and cost savings compared to traditional methods (rodents, microsomes, etc.)

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Metrohm
Sulfur and halide determination by combustion ion chromatography
The article describes a highly efficient combustion ion chromatography system (CIC) that is used for the simultaneous trace-level determination of halogens and sulfur in liquid and solid combustible samples. Results obtained from the analysis of a polymer standard as well as a S-benzyl thiouronium chloride and four different fuel samples are presented.

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Key Topic Updates
Current features
When Peaks Collide
Peak Integration that Matches the Efficiency Principles of UHPLC
Computer-unterstützte Methodenentwicklung in der Flüssigchromatografie unter Berücksichtigung von Temperaturgradienten
Multimedia
The latest from CHROMmunity
Molecular Imaging for Localization and Distribution of Proteins, Peptides, Drugs and Metabolites by Mass Spectrometry
Method Development in Packed Column Supercritical Fluid Chromatography

 
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