Pharmaceutical Technology EPR Monthly Issue:
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Pharm Tech
May 18, 2016
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PRODUCTION TRENDS

Next Steps for Investment in Continuous Manufacturing Research

A US government report on advanced manufacturing promotes continuous manufacturing of pharmaceuticals, which has had recent commercial success but faces challenges for widespread adoption.
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Now Online

Developing Cleaning Procedures for Oral Solid-Dose Manufacturing Equipment.
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TROUBLESHOOTING

Choosing Containment Strategies For Highly Potent APIs

Safe handling of HPAPIs requires determining exposure potential and selecting appropriate containment strategies.
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More Troubleshooting

PACKAGING

First-time Packaging Exhibitors Bring Innovations to INTERPHEX

Packaging technologies for serialization, parenteral products, and solid-dosage forms were displayed.
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More Packaging

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EXPERT INTERVIEW

Douglas B. Hausner, PhD, from the Engineering Research Center for Structured Organic Particulate Systems (C-SOPS) based at Rutgers University, discusses rapid process development for solid-dosage drugs using continuous manufacturing.

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Interphex

Editor's Picks

Entegris Introduces Gamma-Stable Single-Use Bags

The Aramus 2D bags from Entegris are a one-layer film construction made with a gamma-stable fluoropolymer material.
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Improved Enclosure for Bottle Rinsing Machines

Fogg Filler’s enclosures for bottle-rinsing machines have improved fume containment and doors with lift-off hinges for maintenance.
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SPONSOR SHOWCASE

World’s Fastest Capsule Filling Machine

Fette Compacting’s new FEC40 Capsule Filler produces up to 400,000 capsules/hr – nearly twice that of any other capsule filler.  This dramatically elevated output is accomplished in a remarkably small footprint, making machine reconfiguration due to floor space unnecessary.  The high performance-to-footprint ratio is due to Fette Compacting’s patented Duplex Concept, which utilizes a mirrored capsule filling process and double-sided discharge.
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Leistritz will host its’ 11th annual Pharmaceutical Extrusion Seminar on June 22-23, 2016 in NJ.
For details or to register see: http://www.alec-usa.com/PES-2016.htm

Note: Leistritz manufactures twin screw extruders and systems for continuous mixing/devolatilization of API's with excipients.

New Silverson High Viscosity In-Line Mixer

The Silverson Ultra Sanitary High-Viscosity In-Line mixer is engineered to process higher viscosity products, such as creams and ointments, while eliminating the need for an auxiliary feed pump. The unique pumping rotor design substantially increases flow capacity.
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Webcast

Continuous Manufacturing of Pharmaceuticals: Scale-up of a Hot-Melt Extrusion Process

On Demand

An understanding of the variable process parameters that have a significant impact on the final pharmaceutical product is necessary to successfully manage a hot-melt extrusion process when using twin-screw extrusion. Experts discuss residence time, mechanical-energy consumption, and other critical parameters, as well as their effects on a scientific approach to process scale-up.
Sponsored by: Thermo Fisher Scientific

more webcasts

EVENTS

BIO International Convention

June 6–9, 2016 | San Francisco, CA

ISPE/FDA/PQRI Quality Manufacturing Conference

June 6–8, 2016 | Bethesda, MD

more events

eBOOK

Solid Dosage Drug Development and Manufacturing

This ebook reviews methods to address quality issues for APIs, excipients, and intermediates; analysis methods for elemental impurities and continuous powder processing; modeling tools to improve workflows, and methods to improve tablet compression.

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