Build your pharma development and manufacturing knowledge base with the latest whitepapers, application notes, posters, and other educational resources from bio/pharma industry suppliers.

Objective Characterization of Liposomes

Vironova

Liposomal physicochemical characteristics are objectively and accurately measured by using cryo-transmission-electron-microscopy (TEM) in combination with designated image analysis software. Vironova analyizing software (VAS) enables reproducible, semi-automated particle detection, and classification. Liposome analysis includes size distribution, circularity, level of packaging, lamellarity, and lipid bilayer thickness.

Effect of Extrusion Parameters on Solid Dispersions

C. Martin, J. DiNunzio, J.M. Keen, A. Machado, J.W. McGinity, H. Sandhu; Leistritz Extrusion

The objective of this research is to investigate the extrusion process space in co-rotating and counter-rotating extruders, which is critical to ensure the properties of pharmaceutical solid dispersions.

Pneumatic Conveying: Considerations for Powders Difficult to Move

David Kennedy; Vac-u-Max

Some challenges when working with difficult to move powders include getting them into the conveying line from the pick-up point, feeding them at a constant rate, and getting the powder to discharge from the material receiver.

Comparative Human in-vivo study Using Overencapsulated Capsules

Sven Stegemann, Sudershan Vishwanath, Ravi Kumar, Dominique Cade, Missy Lowery, Keith Hutchison, Michael Morgen, Aaron Goodwin, Chang Lee; Capsugel

A comparative investigation was performed using in-vitro dissolution, PK simulation, and human bioequivalence comparing an IR fixed dose combination compressed caplet containing three different rapidly-absorbed drugs over-encapsulated with gelatin capsules, and the same caplet over-encapsulated with HPMC capsules made by a thermo-gelation process.

A Guide to Applying the Four Pillars of ICH Q10

Tim Lozier; ETQ

Learn about the basics of the ICH Q10 model, the four pillars of ICH Q10 and how to apply them, and how the quality management system ensures ICH Q10 compliance.

Pharmaceutical Cleaning Validation

Malcolm McLaughlin; Alconox, Inc.

A comprehensive description of how to perform cleaning validations in the pharmaceutical industry. This whitepaper focuses on the calculations as well as the process.

Combatting Product Diversion with the Mighty Microtag

Peter Wong; TruTag Technologies, Inc.

Unauthorized product diversion directly attacks your bottom line and erodes patient safety. Learn how on-dose authentication can safeguard your drug products, provide key business informatics, and improves your financials.