Pharmaceutical Technology EPR Monthly Issue:
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Pharm Tech
December 20, 2017
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PRODUCTION TRENDS

Manufacturing Microparticles in a Single Step

A Q&A with Orbis Biosciences discusses how their Optimµm Platform creates microparticulate dosage forms with controlled-release and taste-masked properties in a single manufacturing step.
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Establishing an Effective Data Governance System: comply with regulatory expectations for data integrity.
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PACKAGING

Standardizing Serialization

Implementation of the Packaging Serialization Standard cuts serialization costs, shortens deployment time, and expedites compliance with anticounterfeiting regulations.
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More Packaging


EQUIPMENT ENHANCES SOLUBILIZATION: FROM THE PHARM TECH ARCHIVE

Particle Engineering for Bioavailability Enhancement

Aseptic spray drying can be used to engineer unique particle characteristics.
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Enhancing Dissolution of Poorly Soluble Drugs through Jet-Milling

The authors discuss a novel particle engineering technology based on mechano-chemical activation.
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Micronization as a Bioavailability Enhancement Tool

Piero Iamartino, R&D director at Micro-Macinazione, provides insights on the role of micronization in pharmaceutical manufacturing.
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A Practical Guide to Hot-Melt Extrusion Scale-Up for Pharmaceutical Applications

The author discusses various aspects of the hot-melt extrusion process and outlines a practical approach to scale-up.
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Understanding Dissolution Testing

Industry experts discuss best practices for dissolution testing of poorly soluble, immediate-release, and controlled-release formulations and the different analytical approaches used.
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Salt Selection in Drug Development

The selection of an appropriate salt form for a potential drug candidate is an opportunity to modulate its characteristics to improve bioavailability, stability, manufacturability, and patient compliance.
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Editor's Picks

Self-Calibrating Temperature Sensor Prevents Undetected Drift

The Endress+Hauser iTHERM TrustSens hygienic RTD self-calibrates to verify in-line that the sensor is working as designed.
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Feeders for Continuous Processing

The Coperion K-Tron K3-PH-ML-D4-QT35 feeder design is suited for multi-feeder clustering in a variety of continuous processes, including direct compression, continuous extrusion, wet and dry granulation, and continuous coating, as well as traditional batch processes.
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SPONSOR Showcase

Leistritz manufactures twin screw extruders and systems for continuous mixing/devolatilization of API's with excipients. Lab scale and production scale equipment is available, and applications include melt extrusion and granulation. A variety of upstream and downstream equipment is available. Services include a process NJ development laboratory and ongoing training/workshops.
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Savillex Corporation manufactures the Purillex(TM) line of fluoropolymer bottles. Available in both PFA and FEP, Purillex bottles are manufactured in a cleanroom environment using a proprietary stretch blow molding process. This proprietary process provides several key benefits, including superior long term sealing, lower trace metal background and greater reproducibility. The bottles are available in sizes up to 2 Liters.
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UPCOMING WEBCAST

Considerations for Launching a Biopharm Company in 2018
Live Webcast: Monday, January 8, 2018 at 10am EST | 3pm GMT | 4pm CET
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ON DEMAND WEBCASTS

Risk Assessment and Testing Requirements for Elemental Impurities in Pharmaceutical Products
On Demand
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The Journey to a Successful Biologic License Application
On Demand
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Partnership of Chemical Engineers and Chemists Optimizes Process Development
On Demand
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EVENTS

IFPAC

Feb. 11–14, 2018 | Bethesda, MD


ISPE Facilities of the Future Conference

Feb. 20–22, 2018 | Bethesda, MD


more events

eBOOK

Vaccine Development and Manufacturing 2017 eBook

Vaccines—from childhood and influenza immunizations, to epidemic prevention, to cancer and therapeutic treatments—present unique development challenges. In this Vaccine and Manufacturing eBook, the editors explore development and manufacturing options to make vaccines more accessible.


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