Pharmaceutical Technology ePT Weekly
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PharmTech
November 15, 2018
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In this issue:

Split Congress to Attack Drug Pricing

Innovations in Prefilled Syringes for Biologic Drugs

Don't Let CMC Oversights Derail Drug Development


Top Stories

Sanofi, Denali Therapeutics in $1-Billion Deal for Neurologic Drugs

The companies will develop treatments for a range of neurological and inflammatory diseases.
/ read more /


Single-use and IIoT Solutions Expected to Reduce Costs and Enhance Production Efficiency

Experts believe that the contract development and manufacturing organization market will reach $17.38 billion by 2022, with disruptive business models using Industrial Internet of Things (IIot) and single-use technologies proving more profitable and efficient in the long term.
/ read more /

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Industry News

Survey Predicts Drug Product Formulation Recognition and Increasing Budgets

Formulation issues cause significant drug project delays and project failures, according to a 2018 survey conducted by Informa Pharma Intelligence, Rentschler Biopharma, and LEUKOCARE.
/ read more /


Be The Match BioTherapies Launches Program for Faster Cell Facility Onboarding

The new program will provide cell and gene therapy companies a more efficient way to ensure quality compliance across collection center networks and to minimize quality system audit burden on these centers.
/ read more /


More Industry News
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Supplier News

Thermo Fisher Opens Newly Expanded Facility in Maryland

The expanded Frederick, MD, site will help meet global demand for diagnostic instruments and cell and gene therapies for clinical trials.
/ read more /


GE Healthcare Manufactures Single-Use Consumables in China

GE Healthcare will collaborate with Wego Pharmaceutical in China for local production and supply of GE Healthcare's Fortem single-use consumables.
/ read more /


More Supplier News

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The future of pharmaceutical chemical imaging
Renishaw's RA802 Pharmaceutical Analyser offers scientists a step change in vibrational spectroscopy-based imaging techniques. Three of the most common complaints about conventional Raman microscopy and infrared microscopy (IR microscopy) systems are sample focus, speed of analysis and ease-of-use. The RA802 Pharmaceutical Analyser combines Renishaw's proprietary LiveTrack™ and StreamLine™ technologies to generate chemical images up to 150 times faster than conventional methods.
Learn more

Bio/Pharma News

Shire Wins ISPE Facility of the Year Award

The International Society for Pharmaceutical Engineering (ISPE) named Shire as the ISPE 2018 Facility of the Year Awards Overall Winner for a facility integration project in Los Angeles, CA.
/ read more /


AbbVie Signs Patent License with Momenta for Humira Biosimilar

AbbVie will grant Momenta license to launch a biosimilar to AbbVie's Humira.
/ read more /


More Bio/Pharma News

Regulatory News

Split Congress to Attack Drug Pricing

Leaders of the two parties are open to challenging the status quo on drug costs and spending.
/ read more /


FDA Modernizes Inspection of Sterile Products

The agency is developing a new way to assess, record, and report data from surveillance and preapproval inspections of sterile drugs.
/ read more /


More Regulatory News

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THE MOST FLEXIBLE SOLUTION, HANDLING ALL FORMATS OF READY-TO-USE COMPONENTS
INJECTA's flexible handling system defines new quality standards, performing 100% in-line quality control. The most advanced robotic system, replacing conventional component handling, saves time, avoids glass-to-glass contact, provides safe and gentle manipulation, minimizes human interventions and automatically rejects single non-conforming products.
INJECTA. THE ULTIMATE CHECKMATE.


FEATURED TOPICS

DRUG DEVELOPMENT

Don't Let CMC Oversights Derail Drug Development

Experts share best practices, and war stories, for a crucial but often underappreciated part of drug development.
/ read more /

FACILITIES

Multi-Purpose Biopharmaceutical Manufacturing Facilities Part II: Large-Scale Production

Barrier materials, scavengers, and good seal integrity maximize shelf life of oral solid-dosage drug packaging.
/ read more /



MANUFACTURING

Design Space Characterization and Risk Assessment Through Mechanistic Modeling

Mechanistic process and product modeling turns data into knowledge that can be extrapolated with known confidence for design space characterization and risk assessment.
/ read more /

FORMULATION

Innovations in Prefilled Syringes for Biologic Drugs

As biologic drugs grow increasingly complex, drug delivery mechanisms such as prefilled syringes are being adapted to meet the challenges.
/ read more /


UPCOMING WEBCAST

Utilizing Spray-Dried Dispersion Technology for Bioavailability Enhancement: Overview and Case Studies
Thursday, November 15, 2018 at 11am EST|8am PST|4pm GMT|5pm CET
Register now


ON DEMAND WEBCASTS

Validating H2O2 Bio-Decontamination in Rooms and Isolators
On Demand
Learn more


Insoluble APIs Scaring You? Don't be Afraid of Nanoparticles!
On Demand
Learn more


Planning Successful Launches of Complex Drug Products
On Demand
Learn more


Sterility Testing: Best Practices and Use of Isolator Technology
On Demand
Learn more


Successfully Navigating the Analytical Environment of Complex Generic APIs
On Demand
Learn more


Events

Twin Screw Extrusion Workshop

November 28–29, 2018

IVT's Annual Laboratory Week

December 3–5, 2018

2018 ISPE Biopharmaceutical Manufacturing Conference

December 10–12, 2018

more events

eBOOKS

Biologics and Sterile Drug Manufacturing 2018

This ebook covers novel technologies for the formulation, manufacture, purification, and delivery of sterile small- and large-molecule drugs, including single-use systems, facilities and equipment, contamination issues, and process analytics.

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