In this issue: News, interviews, and articles on advances in building effective supply chains, pharmaceutical ingredients manufacturing, and outsourcing developments.
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Supply Chain Updates
Acute Need for Supply Chain Transparency
By Cynthia Challener
Biopharma manufacturers must reduce the risk in their complex supply chains.
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Moving Toward a Safer Supply Chain
By Susan Haigney
FDA’s Secure Supply Chain Pilot Program, RX-360, and other industry efforts advance actions to secure the drug supply chain.
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API Synthesis & Manufacturing
Steady Progress Toward Continuous Flow API Synthesis
By Cynthia Challener, PhD
The pharma industry makes slow, but steady moves toward commercial-scale continuous processes for small-molecule API manufacturing.
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Lyophilization Cycle Design and Scale Up – Practical Methodologies for Developing Cycles
On Demand Webcast
Register Free at:  www.pharmtech.com/cycles
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Analytical Challenges and Case Studies in Method Development for Fixed-Dose Combinations
On Demand Webcast
Register Free at:  www.pharmtech.com/method_development
Outsourcing
When Payers Refuse to Cover New Drugs, CMOs Take a Hit
By Jim Miller
More health systems are saying “no” to reimbursements for new drugs; CMOs must adjust strategies.
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