Pharmaceutical Technology Sourcing and Management Monthly Issue:
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Pharm Tech
December 2015, Volume 11 Issue 12
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In This Issue

Outsourcing Update
Contract Services Update
APIs and Excipients Update
Supply Chain Update

In the Lab

“A Hit for Every Target” and Changing the Model for Pharma Innovation

As 3-D screening and lab automation improve lead optimization, open collaborative models are breaking down long-established walls. Will the industry redefine the way it handles R&D?
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Allotrope Foundation Releases Allotrope Framework 1.0

GSK will implement the Allotrope Framework for use in drug substance release and stability testing.
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Drug Development Application Handbook

A compilation of technical articles from the magazine's archives and application notes, technical information, and educational materials from the handbook's sponsors.

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Instrument Manufacturers Collaborate on Interoperability

Agilent Technologies and Thermo Fisher Scientific exchange instrument control drivers and software support.
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Shimadzu’s Nexera UC Wins R&D 100 Award

The Nexera UC Unified Chromatography System from Shimadzu Scientific Instruments was recognized with an R&D100 award.
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HTS Reader Features Three Light Sources

BMG LABTECH announces the release of a reference multi-mode HTS reader at SLAS in January 2016.
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Lab Reactor Designed for Scale-up

The ReactoMate Datum controlled lab reactor system accommodates a range of vessel sizes.
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Instrument Measures Endotoxins at Point of Use

Charles River offers the Endosafe nexgen-PTS endotoxin testing system.
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Vertical Diffusion Cell Test System

Copley Scientific’s new Vertical Diffusion Cell Test System Model HDT 1000 comprises a compact unit with 10 test stations that enables the precise control of test conditions.
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Software Corrects Spectra Data

KnowItAll spectroscopy software from Bio-Rad Laboratories corrects differences in spectra data.
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Outsourcing Update

CMOs Lead Ongoing Drive for Single-Use Adoption

Better process development is creating industry benchmarks for bioprocessing.
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Contract Services Update

Romaco Acquires Medipac AB and Extends Position in Effervescent Tablets Sector

With the acquisition of Medipac’s tube filling assets for effervescent tablets, Romaco can now offer the complete line configurations for effervescent tablets.
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Cobra Biologics to Scale Production of Growth Hormone

The University of Sheffield has appointed Cobra Biologics to advance novel fusion protein technology into Phase 1 clinical trials.
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Catalent Expands Biologics Capabilities

Expansions at Catalent’s Kansas City, MO, and Madison, WI facilities made in response to industry demand.
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Baxter Expands Fill-Finish Facility

Baxter expands capacity for lyophilized cytotoxic oncology therapies at its fill/finish facility in Halle, Germany.
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GRAM Adds Board Member

Industry veteran Mark Kontny joins board of directors at Grand River Aseptic Manufacturing.
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APIs and Excipients

Researchers Identify Advances for Heterocyclic Chemistry

Multi-component coupling reactions for the generation of heterocycles in fewer steps, and reduced processing times, cost, and waste are attracting interest.
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FDA Approves Ash Stevens as API Manufacturer for Takeda’s Multiple Myeloma Drug

Ash Stevens has received FDA’s approval to manufacture Takeda’s multiple myeloma drug, ixazomib, at its facility in Riverview, Michigan.
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BASF Starts Up Specialty Amines Plant

BASF’s new multi-product amines plant in Ludwigshafen, Germany meets growing demand for amines in various applications, including pharmaceuticals.
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Supply Chain Update

Pharma Supply Chains: Contingency Planning Not Yet a Priority, Survey Says

UPS’ 2015 “Pain in the Chain” survey suggests that pharma companies are getting better at product protection, cold chain and regulatory compliance, but need to improve cost control and planning for unexpected events.
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System Automates Traceability

The Safe Chain Track and Trace System automates traceability for supply chain security.
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Lufthansa Cargo Offers CSafe Containers

CSafe partners with Lufthansa Cargo in dedicating a fleet of RKN containers to Cool/td-Active service offering.
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