Biopharmaceutical Manufacturers Look for Flexibility
Could flexible manufacturing change the standards for biopharmaceutical production? To find out, Equipment and Processing Report talked to James Robinson, vice-president of technical and quality operations at biotechnology company Novavax (Rockville, MD).
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Large-Scale Protein Production with a Cell-Free System
The authors sought to improve the productivity of protein synthesis by using a highly active cell-free extract from Escherichia coli and by optimizing buffer conditions and shaking conditions.
>>Coming Soon: In an upcoming issue of Pharmaceutical Technology, new columnist Eric Langer will describe how factors such as capacity utilization, batch-failure rates, outsourcing, and disposables usage are changing in the biopharmaceutical industry. To participate in the survey that will be the basis of his analysis,
click here.
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Malvern’s (Malvern, England) OmniSEC software supports gel-permeation chromatography and size-exclusion chromatography in quality-assurance applications.
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The Hüttlin HDGC fluid bed from the OYSTAR USA Process Division (Fairfield, NJ) allows operators to perform fluid-bed drying, granulation, and coating in one product container. |
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Clean room strap hoists for Class 10,000 environments.
All external metal components are polished stainless steel. Polypropylene/nylon lifting strap avoids contamination experienced with chain or wire rope. Units up to 4000 lbs. Full line of stainless jib cranes, floor cranes, hoists, and trolleys for pharmaceutical use. See us at Interphex booth 101.
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Kavon Filter Products
Fluid-bed dryer bags
Kavon provides custom replacement fluid-bed dryer bags for US and European equipment models. The bags are appropriate for wet granulation, dry filtration, and wet and dry coating applications. The company offers flexible 1–4-bag systems in various
fabrics choices
and also repairs bags. Kavon Filter Products, Wall Township, NJ ¦ www.kavonfilter.com ¦ tel. 732.938.3135
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New Brighter Cordless Tank Light from Eagle Stainless
110 Lumens of light from portable LED light provides ample illumination of tanks and vessels.
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Spirax Sarco, Inc.
The BT6-B Sanitary Thermostatic Steam Trap attains large CIP/SIP condensate discharge capacities with minimal back-up and sub-cooling. The trap opens approximately 3.6°F (2°C) below steam temperature at discharge pressures of
36 psig (2.5 barg) or less. Its ball-shaped valve and seat promote high-capacity flow and free drainage across the entire load range.
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- The VM-Series of Class 100 cleanroom robots from DENSO (Long Beach, CA) are six-axis articulated, feature reaches of 1000–1300 mm, and operate at standard cycle times of 0.89–0.95 s.
- NewAge Industries (Southampton, PA) offers Prolite polypropylene tubing, which has high chemical and corrosion resistance, low moisture absorption, and high dielectric strength.
- The third generation Mobile Data Acquisition Platform from MODA Technology Partners (Wayne, PA) is designed to enable quality-control organizations to automate their manufacturing process and encourage the adoption of green initiatives by reducing the need for paper-based environmental-monitoring programs.
- Mettler Toledo’s (Columbus, OH) IND690 terminal is suitable for weighing active ingredients and excipients for capsule formulation.
- The GFM Pro Flowmeter from Thermo Fisher Scientific (Milford, MA) is designed for continuous real-time measurement of gas flows and to ensure accurate and reproducible chromatography.
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- Feb. 1–2: Pharmapack 2010 (Paris). This major European event is dedicated to innovations in packaging and delivery packaging for the pharmaceutical industry. Pharmapack 2010 will welcome the key players in the sector. More than 2200 decision makers from pharmaceutical and biotechnology laboratories, health institutions, and authorities will be present.
- Feb. 1–2: BIOMEDevice Europe 2010 (Paris). BIOMEDevice Europe brings together professionals from leading biotechnology, medical-device, and pharmaceutical companies involved in the development and manufacturing of combination products. It offers a networking platform to key executives, engineers, and researchers looking for new partnering and enabling technologies for the future development of combination products.
- Feb. 10–12: QA–QC Strategy for Biopharmaceuticals and Biologics (Malvern, PA). This three-day course is designed for management and professional staff involved in quality-assurance (QA) and quality-control (QC) support for biologics and biopharmaceuticals. This course will be of particular interest to QA and QC personnel (lower-level and management), regulatory-affairs, manufacturing, process-development, and analytical-development staff.
- Feb. 23–24: Second Annual Disposable Solutions for Biomanufacturing (London). This event will update attendees about developments in single-use systems within bioprocessing and manufacturing.
- Feb. 25: Aseptic Process Simulation (Berlin). Regulators and industry experts will discuss how to address requirements defined in the revised Annex 1 and other guidelines. Attendees will learn how to plan and execute compliant aseptic-process simulation exercises. Group exercises will help attendees gain a better understanding of aseptic processes.
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| PharmTech
Poll: |
>>Pharma's Economic Recovery
When do you think the pharmaceutical industry will experience an economic recovery? |
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