Pharm Tech’s EPR: Robotic filling systems to maximize output

January 2012

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Robots' Role in Flexible Fill–Finish Lines
The pharmaceutical industry has a history of developing innovative medicines and novel drug-delivery systems, but not all of its manufacturing processes use cutting-edge technologies. Demands to increase productivity in fill–finish lines are fueling the arguments of proponents of robotic automation to expedite manufacturing.

Common Equipment-Design Pitfalls That Impair Cleaning
Equipment designed correctly will avoid the above pitfalls, thus facilitating safe and cost-efficient cleaning. The more cleaning action is applied on all product-contact surfaces, the easier and quicker system cleaning will be.

>>Coming Soon: For an analysis on the latest development on cold-chain technologies and capabilities, see the February issue of Pharmaceutical Technology.

Increasing the Life-Span of a Probe to Cover a Warranty Period

I work in a quality control laboratory and use a pH meter with a single-junction reference probe to test samples taken from various pharmaceutical (drug) production lines. The probe I use has a six-month warranty. It slowly stops working after just a couple weeks. I am replacing it once a month. We make sure to store it correctly according to the manufacturer's specifications and even use probe cleaner at the end of each shift to ensure that it stays clean. What can I do to increase the lifespan to at least cover the warranty period?

Editor's Pick product

ACS Valves’s Quick-Clean series of rotary airlock valves is designed to aid users in achieving regulatory compliance.

Terra Universal’s cleanrooms are suitable for compounding sterile injectables and other preparations in accordance with USP <797> standards.

Fette Compacting America Inc Fette Compacting now offers the FE55, a tablet press that delivers unprecedented levels of productivity, flexibility and availability. The FE55 is clad in easily-detachable, FDA-certified high-performance polymer panels and offers 360-degree access. The FE55 has the ability to produce single- and double-layer tablets and direct pressing – the only machine of its compact size to offer all three capabilities. Click here for more info.

Chemsultants International Providing Consulting, Product Development, and Testing of Adhesives and Specialty Coatings for the Pharmaceutical Industry. http://www.chemsultants.com/markets/medical-pharmaceutical.aspx

TopLine Process Equipment Company Top-Flo^® SV2 sample valves are specifically engineered to be the finest in the industry and incorporate many features and benefits not found on other sampling valves. Top-Flo^® SV2 sampling valves come standard with minimal internal deadleg area designed into each valve, keeping hold up volume to a minimum for accurate samples every time. Right angle or In-Line models available from stock in sizes 1/2'' to 6'' in a variety of inlet/outlet connections. www.toplineonline.com

Camfil Farr’s FarrVac Junior vacuum uses HEPA filtration and operates without compressed air.
Cognex’s DataMan 8000 ID scanner offers extended range cord-free code reading applications.
Horizon Technology’s SmartPrep Extractor automates manual cartridge-based solid-phase extraction methods.
National Bulk Equipment’s bulk material handling system reduces operator interaction.
Yokogawa Y-Plant Alert system offers alarm event sequence of event recording and annunciator functions.

Feb. 2–3: Computer System Validation - Reduce Costs and Avoid 483s (London, UK). This interactive two-day course explores proven techniques for reducing costs associated with implementing, using, and maintaining computer systems in regulated environments.
Feb. 14–17: Informex (New Orleans, LA).This trade show offers exhibitors and attendees a glimpse of what is happening domestically and internationally in fine chemicals and contract API manufacturing.
Feb. 15–16: Pharmapack (Paris, France). This exhibition will bring together more than 250 companies representing the leading designers, manufacturers, and suppliers of drug packaging and delivery systems.

PharmTech Poll: API Manufacturing

What is the most important change that has influenced chemical API manufacturing during the past 10 years?

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